Hairy cell leukemia
Help me code for diagnosis year :
Neoplasm in bone marrow and peripheral blood composed of small B lymphoid cells with oval nuclei and abundant cytoplasm with hairy projections, diffusely infiltrating bone marrow and splenic red pulp.
The diagnosis is best made on bone marrow. HCL infiltrates are found in the red pulp of the spleen. The white pulp is typically atrophic. The liver may show infiltrates of hairy cells, predominantly in the sinusoids. Lymph node infiltration may occur especially in advanced disease.
Treatment options will depend on the following: Number of hairy cells vs healthy blood cells in the blood and bone marrow, swollen spleen, presence of infection or whether the leukemia has recurred (come back) after previous treatment. Treatment often results in long-lasting remission
Hairy Cell leukemia has the following groups:
1. Untreated Hairy Cell Leukemia: newly diagnosed
2. Progressive Hairy Cell Leukemia: previous treatment with either chemotherapy or splenectomy and the following occur: increase in number of hairy cells in the blood or bone marrow OR number of red blood cells, white blood cells or platelets is lower than normal
3. Relapsed Hairy Cell Leukemia: Leukemia has come back after treatment
4. Refractory Hairy Cell Leukemia: Nonresponsive to treatment