Help me code for diagnosis year :
There are several variants of SM:
1. [Indolent systemic mastocytosis (ISM) is NOT reportable; it includes subtypes bone marrow mastocytosis and smoldering systemic mastocytosis and would be coded as 9741/1 in the WHO classification; the mast cell burden is very low (<1% of nucleated bone marrow cells) and life expectancy is normal.]
2. Aggressive systemic mastocytosis (ASM) - Organomegaly and impaired organ function are usually present. There may be weight loss caused by malabsorption in the GI tract due to mast cell infiltrates, or skeletal involvement with large osteolytic lesions and/or pathologic fractures. There are usually no skin lesions. A type of ASM, lymphadenopathic mastocytosis with eosinophilia, features progressive lymphadenopathy with peripheral blood eosinophilia, often with extensive bone involvement and hepatosplenomegaly. Genetically cases classified as ASM have no PDGFRA rearrangement. Survival is a few years.
3. Systemic mastocytosis - associated clonal hematological non-mast-cell lineage disease (SM-AHNMD), a myeloid or lymphatic malignancy is diagnosed with the SM; CMML (9945/3) is the most common associated disease. The prognosis is usually dominated by the non-mast cell malignancy.