SEER Stat Fact Sheets: Anal Cancer

Statistics at a GlanceShow More

At a Glance

  • Estimated New Cases in 2016 8,080
  • % of All New Cancer Cases0.5%
  • Estimated Deaths in 2016 1,080
  • % of All
    Cancer Deaths
    0.2%

Percent Surviving
5 Years

66.4% 2006-2012

Number of New Cases and Deaths per 100,000: The number of new cases of anal cancer was 1.8 per 100,000 men and women per year. The number of deaths was 0.2 per 100,000 men and women per year. These rates are age-adjusted and based on 2009-2013 cases and deaths.

Lifetime Risk of Developing Cancer: Approximately 0.2 percent of men and women will be diagnosed with anal cancer at some point during their lifetime, based on 2011-2013 data.

Survival StatisticsShow More

How Many People Survive 5 Years Or More after Being Diagnosed with Anal Cancer?

Relative survival statistics compare the survival of patients diagnosed with cancer with the survival of people in the general population who are the same age, race, and sex and who have not been diagnosed with cancer. Because survival statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to treatment can vary greatly.

66.4%

Percent Surviving
5 Years

66.4%

Based on data from SEER 18 2006-2012. Gray figures represent those who have died from anal cancer. Green figures represent those who have survived 5 years or more.

Additional Information

Cancer stage at diagnosis, which refers to extent of a cancer in the body, determines treatment options and has a strong influence on the length of survival. In general, if the cancer is found only in the part of the body where it started it is localized (sometimes referred to as stage 1). If it has spread to a different part of the body, the stage is regional or distant. The earlier anal cancer is caught, the better chance a person has of surviving five years after being diagnosed. For anal cancer, 48.1% are diagnosed at the local stage. The 5-year survival for localized anal cancer is 80.7%.

Percent of Cases & 5-Year Relative Survival by Stage at Diagnosis: Anal Cancer
Percent of Cases by Stage
  • Localized (48%)
    Confined to Primary Site
  • Regional (32%)
    Spread to Regional Lymph Nodes
  • Distant (13%)
    Cancer Has Metastasized
  • Unknown (7%)
    Unstaged
48% localized; 32% regional; 13% distant; 7% unknown
5-Year Relative Survival
80.7% localized; 60.8% regional; 30.4% distant; 60.3% unstaged

SEER 18 2006-2012, All Races, Both Sexes by SEER Summary Stage 2000

Additional Information

Number of New Cases and DeathsShow More

How Common Is This Cancer?

Compared to other cancers, anal cancer is rare.

Common Types of Cancer Estimated New
Cases 2016
Estimated
Deaths 2016
1. Breast Cancer (Female) 246,660 40,450
2. Lung and Bronchus Cancer 224,390 158,080
3. Prostate Cancer 180,890 26,120
4. Colon and Rectum Cancer 134,490 49,190
5. Bladder Cancer 76,960 16,390
6. Melanoma of the Skin 76,380 10,130
7. Non-Hodgkin Lymphoma 72,580 20,150
8. Thyroid Cancer 64,300 1,980
9. Kidney and Renal Pelvis Cancer 62,700 14,240
10. Leukemia 60,140 24,400
- - -
26. Anal Cancer 8,080 1,080

Anal cancer represents 0.5% of all new cancer cases in the U.S.

0.5%

In 2016, it is estimated that there will be 8,080 new cases of anal cancer and an estimated 1,080 people will die of this disease.

Anal cancer is slightly more common in women than men. Infection with human papillomavirus (HPV) has been associated with this cancer. The number of new cases of anal cancer was 1.8 per 100,000 men and women per year based on 2009-2013 cases.

Percent of New Cases by Age Group: Anal Cancer
0.0% under 20; 1.1% 20-34; 5.9% 35-44; 23.9% 45-54; 28.4% 55-64; 20.7% 65-74; 13.8% 75-84; 6.2% 85 and older

Anal cancer is most frequently diagnosed among people aged 55-64.

Median Age
At Diagnosis

61

SEER 18 2009-2013, All Races, Both Sexes

Number of New Cases per 100,000 Persons by Race/Ethnicity & Sex: Anal Cancer
MalesFemales
  • Male 1.5All RacesFemale 2.1
  • Male 1.5WhiteFemale 2.3
  • Male 2.1BlackFemale 1.7
  • Male 0.5Asian /
    Pacific Islander
    Female 0.6
  • Not Shown, <16 casesAmerican Indian /
    Alaska Native
    Female 1.1
  • Male 0.9HispanicFemale 1.5
  • Male 1.6Non-HispanicFemale 2.2

SEER 18 2009-2013, Age-Adjusted

The number of deaths was 0.2 per 100,000 men and women per year based on 2009-2013 deaths.

Percent of Deaths by Age Group: Anal Cancer
0.0% under 20; 0.6% 20-34; 5.1% 35-44; 18.5% 45-54; 25.7% 55-64; 21.4% 65-74; 17.4% 75-84; 11.2% 85 and older

The percent of anal cancer deaths is highest among people aged 55-64.

Median Age
At Death

65

U.S. 2009-2013, All Races, Both Sexes

Number of Deaths per 100,000 Persons by Race/Ethnicity & Sex: Anal Cancer
MalesFemales
  • Male 0.2All RacesFemale 0.3
  • Male 0.2WhiteFemale 0.3
  • Male 0.3BlackFemale 0.2
  • Male 0.1Asian /
    Pacific Islander
    Female 0.1
  • Not Shown, <16 casesAmerican Indian /
    Alaska Native
    Not Shown, <16 cases
  • Male 0.1HispanicFemale 0.2
  • Male 0.2Non-HispanicFemale 0.3

U.S. 2009-2013, Age-Adjusted

Trends in RatesShow More

Changes Over Time

Keeping track of the number of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments.

Using statistical models for analysis, rates for new anal cancer cases have been rising on average 2.2% each year over the last 10 years. Death rates have been rising on average 3.2% each year over 2004-2013. 5-year survival trends are shown below the figure.

More About This CancerShow More

Cancer and the Anus

Gastrointestinal (digestive) system anatomy; shows esophagus, liver, stomach, colon, small intestine, rectum, and anus.
Figure: Anatomy of the Lower Digestive System
Click to enlarge.

Anal cancer is a disease in which malignant (cancer) cells form in the tissues of the anus at the end of the large intestine, below the rectum. The anus is formed partly from the outer, skin layers of the body and partly from the intestine.

Additional Information

More Information

Here are some resources for learning more about anal cancer.

References

All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within:

Howlader N, Noone AM, Krapcho M, Miller D, Bishop K, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2013, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2013/, based on November 2015 SEER data submission, posted to the SEER web site, April 2016.

Suggested Citation

All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.

SEER Cancer Statistics Factsheets: Anal Cancer. National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/statfacts/html/anus.html

This factsheet focuses on population statistics that are based on the US population. Because these statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. To see tailored statistics, browse the SEER Cancer Statistics Review. To see statistics for a specific state, go to the State Cancer Profiles.

The statistics presented in this factsheet are based on the most recent data available, most of which can be found in the SEER Cancer Statistics Review. In some cases, different year spans may be used. Estimates for the current year are based on past data.

Cancer is a complex topic. There is a wide range of information available. This factsheet does not address causes, symptoms, diagnosis, treatment, follow-up care, or decision making, although it provides links to information in many of these areas.