SEER is an authoritative source of information on cancer incidence and survival in the United States. SEER currently collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 28 percent of the U.S. population.
Large B-cell lymphoma rich in T-cells and simulating Hodgkin disease
T-cell rich B-cell lymphoma
This neoplasm is characterized by a limited number of scattered, large, atypical B cells embedded in a background of abundant T cells and frequently histiocytes which are useful for diagnosis.
(This code is effective for cases diagnosed 2010 and later.) THRLBCL mainly affects the lymph nodes but bone marrow, liver and spleen involvement are frequently found at diagnosis. Most patients present at advanced stages (Stage IV with bone marrow involvement). Patients present with fever, malaise, splenomegaly and/or hepatomegaly. This disease is often refractory to chemotherapy. Most frequently treated with CHOP.
If cells are EBV positive, need to reconsider diagnosis (DLBCL). This is an aggressive lymphoma.
Preferred primary sites are listed for this disease in the primary site field; however, involvement in other sites is possible, but rare. If you have confirmation that the only involved site is something other than the preferred primary listed, then code to that primary site.