Nodular sclerosis classical Hodgkin lymphoma

Name
Nodular sclerosis classical Hodgkin lymphoma
ICD-O-1 Morphology
9656/3
Effective 1978 - 1991
ICD-O-2 Morphology
9663/3
Effective 1992 - 2000
ICD-O-3 Morphology
9663/3
Effective 2001 and later
Reportable
for cases diagnosed 1978 and later
Primary Site(s)
C770-C779

Help me code for dx year :

Grade
Code grade specified by pathologist. If no grade specified, code 9
Module Rule
None
Alternate Names
Classical Hodgkin lymphoma, nodular sclerosis, NOS
Classical Hodgkin lymphoma, nodular sclerosis, syncytial variant
Hodgkin disease, nodular sclerosis, NOS
Hodgkin lymphoma, nodular sclerosis, NOS
Nodular sclerosis Hodgkin lymphoma
NS-HL
NSCHL
Definition
Most common subtype of Hodgkin lymphoma. Nodular growth pattern, broad bands of fibrosis, characteristic variant of Reed Sternberg cell. Lacunar cell-abundant clear cytoplasm, sharply demarcated cell membrane; mononuclear, hyperlobated, or multinucleated; smaller nucleoli than in classic RS cells.

Nodular sclerosis classical Hodgkin lymphoma is a subtype of CHL characterized by collagen bands that surround at least one nodule, and Hodgkin and Reed-Sternberg cells with lacunar type morphology.
Abstractor Notes
Nodular sclerosis classical Hodgkin lymphoma (NSCHL) occurs in the mediastinum in 89% of the cases, bulky disease in 54%, splenic and/or lung involvement in 8-10%, bone involvement in 5%, bone marrow involvement in 3%, and liver involvement in 2%. Most patients present with stage II disease. B symptoms are encountered in approximately 40% of cases. NSCHL has a better prognosis than that of other types of CHL. Massive medistinal disease is an adverse prognostic factor.

This is the most common subtype of HL in developed countries. It usually affects females more than males and has a median age of onset at approximately 28 years.

Hodgkin lymphoma, nodular sclerosis, cellular phase 9664/3 is obsolete. Those cases are now coded to this classification, 9663/3.

Preferred primary sites are listed for this disease in the primary site field; however, involvement in other sites is possible, but rare. If you have confirmation that the only involved site is something other than the preferred primary listed, then code to that primary site.
Definitive Diagnostic Methods
Histological confirmation
Immunophenotyping
Genetics Data
None
Immunophenotyping
CD15+
CD30+
CD45-
Treatments
Chemotherapy
Hormone
Radiation
Transformations to
None
Corresponding ICD-9 Codes
201.5 Hodgkin's disease, nodular sclerosis
Corresponding ICD-10 Codes
C81.1 Hodgkin's disease, nodular sclerosis
Corresponding ICD-10-CM Codes (effective October 1, 2015 U.S. only)
C81.1 Nodular sclerosis classical Hodgkin lymphoma
Signs and Symptoms
None
Diagnostic Exams
None
Recurrence and Metastases
None
Epidemiology and Mortality
None