SEER is an authoritative source of information on cancer incidence and survival in the United States. SEER currently collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 28 percent of the U.S. population.
Lymph nodes (C770-C779) are the usual primary sites; however, involvement in other sites is possible. If you have confirmation that the only involved site is something other than the lymph nodes, then code to that primary site. See Module 7.
Most common subtype of Hodgkin lymphoma. Nodular growth pattern, broad bands of fibrosis, characteristic variant of Reed-Sternberg cell. Lacunar cell-abundant clear cytoplasm, sharply demarcated cell membrane; mononuclear, hyperlobated, or multinucleated; smaller nucleoli than in classic RS cells.
Nodular sclerosis classical Hodgkin lymphoma is a subtype of CHL characterized by collagen bands that surround at least one nodule, and Hodgkin and Reed-Sternberg cells with lacunar type morphology.
Nodular sclerosis classical Hodgkin lymphoma (NSCHL) occurs in the mediastinum in 90% of the cases, bulky disease in 54%, splenic and/or lung involvement in 8-10%, bone involvement in 5%, bone marrow involvement in 3%, and liver involvement in 2%.
Most patients present with stage II disease. B symptoms are encountered in approximately 40% of cases. Massive mediastinal disease is an adverse prognostic disease.