Help me code for diagnosis year :
Neoplasm of small B lymphocytes, plasmacytoid lymphocytes, and plasma cells, involving bone marrow, lymph nodes, spleen; usually lacking CD5; serum monoclonal protein of IgM with consequent hyperviscosity symptoms.
Patients with WM have IgM (immunoglobulin M) in their blood and/or bone marrow. IgM is also called IgM monoclonal gammopathy. There will also be an increased number of lymphocytes in the blood. A familial disposition may exist in up to 20% of patients. It tends to be diagnosed at a younger age than other lymphoplasmacytic lymphomas.
Treatment of Waldenstrom macroglobulinemia may include the following:
1. Biologic (immuno) therapy with interferon
4. Proteasome inhibitor
5. Watchful waiting