SEER is an authoritative source of information on cancer incidence and survival in the United States. SEER currently collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 28 percent of the U.S. population.
See Module 7. Lymph nodes (C770-C779) are the usual primary sites; however, involvement in other sites is possible. If you have confirmation that the only involved site is something other than lymph nodes, then code to that primary site.
Most uncommon subtype of Hodgkin lymphoma. Variable morphology, consistent relative predominance of Reed-Sternberg cells and variants with depletion of non-neoplastic lymphocytes. Fibrotic and reticular/sarcomatous subtypes.
Lymphocyte-depleted classical Hodgkin lymphoma (LDCHL) has a predilection for retroperitoneal lymph nodes, abdominal organs, and bone marrow. Compared to other subtypes of CHL, LDCHL presents at a more advanced stage (III-IV) and with B symptoms.
Prior to modern therapy the course of LDCHL was aggressive and it has remained so in some parts of Europe and developing countries.
Per WHO, Hodgkin lymphomas are primarily B-cell lymphomas. If the medical record states B-cell, code 6. Since there are Hodgkin lymphomas that are not B-cell, the default grade is 9 (unknown) where the documentation does not specifically state B-cell.