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Code grade specified by pathologist. If no grade specified, code 9
M3 Module 5: PH10
This is an AML generally showing maturation in the megakaryocyte lineage. This occurs most commonly in infants with Downs Syndrome with a female predominance. This disease is restricted to infants and young children with most cases occuring in the first 6 months of life.
(This code is effective for cases diagnosed 2010 and later. For cases diagnosed prior to 2010 see code 9910/3. ) Most commonly occurs in infants without Downs syndrome. The vast majority of cases present with marked organomegaly, especially hepatosplenomegaly. Patients also have anemia, thrombocytopenia and a moderately elevated white blood count.