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9 - Grade/differentiation unknown, not stated, or not applicable
Refractory anemia with excess blasts in transformation
RAEB-1 (Type 1) and RAEB-2 (Type 2) are defined based on the number of blasts: 1. RAEB-1: 5-9% blasts in bone marrow, < 5% blasts in blood 2. RAEB-2: 10-19% blasts in bone marrow (note if 5-19% blasts in blood and < 10% blasts in marrow, should be RAEB-2 OR RAEB with Auer rods). aka RAEB-T (RAEB in transformation which has ICD-O-3 code of 9984/3)
The principle sites of involvement are the peripheral blood and bone marrow. Any one of the cell types can be low and look abnormal under the microscope.
For MDS diseases (9980, 9982, 9983, 9985, 9986, 9989, 9991, 9992), abstracting each of the subtypes would result in over-counting of the diseases. 1. Code only the first subtype that is diagnosed. 2. Do not change the histology code or create a new abstract for any subsequent specific MDS subtypes
Code 9984/3 in ICD-O-3 is for: RAEB-T (Refractory anemia with excess blast in transformation). This code became obsolete effective 1/1/2010. Any cases noted to be RAEB-T for diagnosis dates 1/1/2010 and forward should be coded to 9983/3.