SEER is an authoritative source of information on cancer incidence and survival in the United States. SEER currently collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 28 percent of the U.S. population.
Code grade specified by pathologist. If no grade specified, code 9
M3 Module 5: PH10
An acute leukemia in which =>50% of the blasts are of megakaryocytic lineage.
This is a rare type of pediatric acute myeloblastic leukemia. Approximately 1/3 of cases are associated with t(1;22)(p13;q13) and 1/3 with Down Syndrome. Children may present with a broad variety of atypical symptoms which may range from minor to life-threatening conditions. Most patients present with fatigue and/or asthenia, which is often accompanied by persistent fever. Severe infections may occur due to the diminished neutrophil count and function. Easy brusing may occur as well as bleeding (epistaxis, oral or gingival bleeding, rectal blood loss, menorrhagia, cerebral hemorrhage). The bleeding disorders result from thrombocytopenia.