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Myelodysplastic syndrome with bi-cytopenia or pancytopenia and dyplastic changes in 10% or more of cells in 2 or more of myeloid cell lines. < 1% blasts in blood, < 5% blasts in marrow, <15% ringed sideroblasts (If > 15%, case should be classified as subtype RCMD-RS) Auer rods not seen, Monocytes in blood < 1 x 109/L
Blood and bone marrow are always involved. At least 2 types of blood counts are low and have an abnormal appearance under the microscope (dysplasia). The number of blasts is less than 5%.
This histology code also includes childhod MDS. MDS is very rare in children. Both the peripheral blood and bone marrow are involved.
For MDS diseases (9980, 9982, 9983, 9985, 9986, 9989, 9991, 9992), abstracting each of the subtypes would result in over-counting of the diseases. 1. Code only the first subtype that is diagnosed. 2. Do not change the histology code or create a new abstract for any subsequent specific MDS subtypes.