Acute myeloid leukemia with t(6;9)(p23;q34); DEK-NUP214

Name
Acute myeloid leukemia with t(6;9)(p23;q34); DEK-NUP214
ICD-O-3 Morphology
9865/3
Effective 2010 and later
Reportable
for cases diagnosed 2010 and later
Primary Site(s)
C421

Help me code for diagnosis year :

Grade
Code grade specified by pathologist. If no grade specified, code 9
Module Rule
M3 Module 5: PH10
Alternate Names
None
Definition
This disease is an AML with or without monocytic features that is often associated with basophilia and multilineage dysplasia. Patients usually present with anemia and thrombocytopenia. White blood cell count is generally lower than other AML types
Abstractor Notes
(This code is effective for cases diagnosed 2010 and later. For cases diagnosed prior to 2010 see code 9861/3.) This AML has a generally poor prognosis. Elevated white blood cell counts are most predictive of shorter overall survival and increased BM blasts are associated with shorter disease free survival. Very limited data available regarding treatment or survival. This type of AML usually presents with anemia and thrombocytopenia and often with pancytopenia. In adults the WBC is generally lower than other AML types. The BM may have morphologic and cytochemical features of any FAB subtype of AML other than acute promyelocytic leukemia and acute megakaryoblastic leukemia.
Definitive Diagnostic Methods
Genetics on bone marrow
Genetics Data
DEK
NUP214
Immunophenotyping
CD13
CD15
CD33
CD34
CD38
CD117
HLA-DR
Myeloperoxidase
Treatments
Stem cell transplant
Transformations to
No Transformations
Corresponding ICD-9 Codes
205.0 Acute myeloid leukemia
Corresponding ICD-10 Codes
C92.0 Acute myeloid leukemia
Corresponding ICD-10-CM Codes (effective October 1, 2015 U.S. only)
C92.0 Acute myeloblastic leukemia
Signs and Symptoms
None
Diagnostic Exams
None
Recurrence and Metastases
None
Epidemiology and Mortality
None