Acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26.2); RPN1-EVI1

Name
Acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26.2); RPN1-EVI1
ICD-O-3 Morphology
9869/3
Effective 2010 and later
Reportable
for cases diagnosed 2010 and later
Primary Site(s)
C421

Help me code for dx year :

Grade
Code grade specified by pathologist. If no grade specified, code 9
Module Rule
M3 Module 5: PH10
Alternate Names
None
Definition
This is an AML that may present de novo or arise from a prior MDS. It is often associated with normal or elevated peripheral blood platelet counts and has increased atypical bone marrow megakaryocytes with mono- or bi-lobated nuclei and associated multilineage dysplasia
Abstractor Notes
(This code is effective for cases diagnosed 2010 and later. For cases diagnosed prior to 2010 see code 9861/3.) Patients most commonly present with anemia and a normal platelet count. Marked thrombocytopenia may also occur. Patients may have a prior MDS or present with splenomegaly. Lymphadenopathy is uncommon.
Definitive Diagnostic Methods
Peripheral blood
Genetics Data
EVl1
MDS1-EV11
RPN1
Immunophenotyping
CD13
CD33
CD34
CD38
HLA-DR
Treatments
Stem cell transplant
Transformations to
No Transformations
Corresponding ICD-9 Codes
205.0 Acute myeloid leukemia
Corresponding ICD-10 Codes
C92.0 Acute myeloid leukemia
Corresponding ICD-10-CM Codes (effective October 1, 2015 U.S. only)
C92.0 Acute myeloblastic leukemia
Signs and Symptoms
None
Diagnostic Exams
None
Recurrence and Metastases
None
Epidemiology and Mortality
None