Acute myeloid leukemia with minimal differentiation

Name
Acute myeloid leukemia with minimal differentiation
ICD-O-3 Morphology
9872/3
Effective 2001 and later
Reportable
for cases diagnosed 2001 and later
Primary Site(s)
C421

Help me code for diagnosis year :

Grade
Code grade specified by pathologist. If no grade specified, code 9
Module Rule
M3 Module 5: PH10
Alternate Names
Acute myeloblastic leukemia
Acute myeloblastic leukemia, minimally differentiated
Acute myeloid leukemia, M0
FAB M0
Definition
An acute leukemia with no evidence of myeloid differentiation by morphology and/or light microscopy cytochemistry. The myeloid nature of the blasts is demonstrated by immunological markers and/or ultrastructural cytochemistry.
Abstractor Notes
This AML has little or no evidence of myeloid differentiation by morphology and light microscopy cytochemistry. The disease is identified by immunophenotyping and/or ultrastructural cytochemistry. Immunophenotyping is essential to distinguish this neoplasm from ALL.
Definitive Diagnostic Methods
Immunophenotyping
Genetics Data
FLT3
RUNX1(AML1)
Immunophenotyping
CD13
CD33
CD34+ (in approx. 70% of cases)
CD38
CD117
HLA-DR+ (in approx. 70% of cases)
Treatments
Chemotherapy
Stem cell transplant
Transformations to
No Transformations
Corresponding ICD-9 Codes
205.0 Acute myeloid leukemia
Corresponding ICD-10 Codes
C92.0 Acute myeloid leukemia
Corresponding ICD-10-CM Codes (effective October 1, 2015 U.S. only)
C92.0 Acute myeloblastic leukemia
Signs and Symptoms
None
Diagnostic Exams
None
Recurrence and Metastases
None
Epidemiology and Mortality
None