SEER is an authoritative source of information on cancer incidence and survival in the United States. SEER currently collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 28 percent of the U.S. population.
A neoplasm of lymphoblasts committed to the B lineage whose blasts contain <46 chromosomes. A stricter definition of <45 chromosomes, and possibly even <44 chromosomes more accurately reflects the clinical pathologic entity.
This disease is seen in both children and adults, although near haploid ALL (23-29 chromosomes) appears limited to childhood.
(This code is effective for cases diagnosed 2010 and later. For cases diagnosed prior to 2010 see codes: 9728/3 [lymphoma] or 9836/3 [leukemia].)
Hypodiploid ALL has a poor prognosis. The prognosis for this disease depends on the number of chromosomes; those with 44-45 chromosomes have the best prognosis. Patients may fare poorly even if they do not have residual disease following therapy.