B lymphoblastic leukemia/lymphoma with hyperdiploidy

Name
B lymphoblastic leukemia/lymphoma with hyperdiploidy
ICD-O-3 Morphology
9815/3
Effective 2010 and later
Reportable
for cases diagnosed 2010 and later
Primary Site(s)
See Abstractor Notes and Module 4: Rules PH7, PH8

Help me code for diagnosis year :

Grade
6 - B-cell
Module Rule
Module 4: PH7, PH8
Alternate Names
ALL with favorable trisomies
High hyperdiploid ALL
Hyperdiploid ALL
Definition
A neoplasm of lymphoblasts committed to the B lineage whose blasts contain >50 and usually <66 chromosomes, typically without translocations or other structural alterations. This leukemia is common in children, accounting for about 25% of cases of B-ALL.
Abstractor Notes
(This code is effective for cases diagnosed 2010 and later. For cases diagnosed prior to 2010 see codes: 9728/3 [lymphomas] or 9836/3 [leukemia].) This leukemia is common in children, accounting for about 25% of cases of B-ALL. It is not seen in infants, and decreases in frequency in older children to the point that it is rare in adulthood. The presenting features are generally similar to those of other patients with ALL. Cases of T-ALL should not be included in this code even though those patients have near tetraploid karyotypes. Immunophenotyping will confirm that the patient has a B-lymphoblastic B-ALL; the genetic testing provides the information needed to classify this neoplasm as a B lymphoblastic leukemia/lymphoma with hyperdiploidy.
Definitive Diagnostic Methods
Bone marrow biopsy
FISH
Flow cytometry
Genetics testing
Karyotyping
Genetics Data
Extra copies of chromosomes 21, X, 14 and 4
Immunophenotyping
CD10+
CD19+
CD34+
CD45 absent
Treatments
Chemotherapy
Stem cell transplant
Transformations to
There are no known transformations
Transformations from
There are no known transformations
Corresponding ICD-9 Codes
204.8 Other lymphoid leukemia
Corresponding ICD-10 Codes
C91.7 Other lymphoid leukemia
Corresponding ICD-10-CM Codes (effective October 1, 2015 U.S. only)
C91.Z Other lymphoid leukemia
Signs and Symptoms
None
Diagnostic Exams
None
Recurrence and Metastases
None
Epidemiology and Mortality
None