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A neoplasm of lymphoblasts committed to the B lineage whose blasts contain >50 and usually <66 chromosomes, typically without translocations or other structural alterations. This leukemia is common in children, accounting for about 25% of cases of B-ALL.
(This code is effective for cases diagnosed 2010 and later. For cases diagnosed prior to 2010 see codes: 9728/3 [lymphomas] or 9836/3 [leukemia].) This leukemia is common in children, accounting for about 25% of cases of B-ALL. It is not seen in infants, and decreases in frequency in older children to the point that it is rare in adulthood. The presenting features are generally similar to those of other patients with ALL. Cases of T-ALL should not be included in this code even though those patients have near tetraploid karyotypes. Immunophenotyping will confirm that the patient has a B-lymphoblastic B-ALL; the genetic testing provides the information needed to classify this neoplasm as a B lymphoblastic leukemia/lymphoma with hyperdiploidy.