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| HCPCS | Generic Name | Brand Name | Strength | SEER*Rx Category | Major Drug Class | Minor Drug Class | Oral (Y/N) | FDA Approval Year | FDA Discontinuation Year | CMS Effective Date | CMS Discontinuation Date | Status |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Q5162 | Denosumab-nxxp | Bildyos/Bilprevda | 1mg | Immunotherapy | Monoclonal Antibody | RANKL | No | 2026 | Mar 18, 2026 | In Use | ||
| C9307 | Linvoseltamab-gcpt | Lynozyfic | 1mg | Immunotherapy | Monoclonal Antibody | BCMA, CD3 | No | 2025 | Jan 12, 2026 | Mar 18, 2026 | In Use | |
| C9308 | Carboplatin (avyxa) | Kyxata | 1mg | Chemotherapy | Alkylating Agent | Platinum Compound | No | 2025 | Jan 12, 2026 | Mar 18, 2026 | In Use | |
| N/A | Ziftomenib | Komzifti | 200mg | Chemotherapy | Enzyme Inhibitor | KMT2A | Yes | 2025 | In Use | |||
| C9306 | Telisotuzumab vedotin-tllv | Emrelis | 1mg | Immunotherapy | Drug Antibody Conjugate | c-MET | No | 2025 | 2026 | Sep 8, 2025 | Jan 12, 2026 | In Use |
| J9072 | Cyclophosphamide (frindovyx) | Frindovyx | 5mg | Chemotherapy | Alkylating Agent | Nitrogen Mustard | No | 2025 | Sep 8, 2025 | In Use | ||
| J9277 | Pembrolizumab and berahyaluronidase alfa-pmph | KEYTRUDA QLEX | 1mg | Immunotherapy | Checkpoint Inhibitor | PD-1 | No | 2025 | Mar 18, 2026 | In Use | ||
| N/A | Taletrectinib | IBTROZI | 272mg | Chemotherapy | Tyrosine Kinase Inhibitor | ROS1, TRKA, TRKB, TRKC | Yes | 2025 | In Use | |||
| N/A | Imlunestrant | Inluriyo | 200mg | Hormonal Therapy | Estrogen Receptor Antagonist | ER⍺ | Yes | 2025 | In Use | |||
| J9184 | Gemcitabine (avyxa) | Avgemsi | 200mg | Chemotherapy | Antimetabolite | Pyrimidine Analog | No | 2025 | Jan 12, 2026 | In Use | ||
| Q5159 | Denosumab-dssb | Ospomyv, Xbryk | 1mg | Immunotherapy | Monoclonal Antibody | RANKL | No | 2025 | Sep 8, 2025 | In Use | ||
| J9278 | Carboplatin (avyxa) | Kyxata | 1mg | Chemotherapy | Alkylating Agent | Platinum Compound | No | 2025 | Mar 18, 2026 | In Use | ||
| J9601 | Linvoseltamab-gcpt | Lynozyfic | 1mg | Immunotherapy | Monoclonal Antibody | BCMA, CD3 | No | 2025 | Mar 18, 2026 | In Use | ||
| N/A | Avutometinib potassium and defactinib hydrochloride | AVMAPKI FAKZYNJA CO-PACK | 0.8mg and 200mg | Chemotherapy | MEK Inhibitor, Tyrosine Kinase Inhibitor | MEK1/2, ERK1/2, KRAS | Yes | 2025 | In Use | |||
| J9275 | Cosibelimab-ipdl | UNLOXCYT | 2mg | Immunotherapy | Checkpoint Inhibitor | PD-L1 | No | 2025 | Jul 9, 2025 | In Use | ||
| J0614 | Treosulfan | Grafapex | 50mg | Chemotherapy | Alkylating Agent | Alkyl Sulfonate | No | 2025 | Sep 8, 2025 | In Use | ||
| N/A | SEVABERTINIB | Hyrnuo | 10mg | Chemotherapy | Tyrosine Kinase Inhibitor | HER2, EGFR | Yes | 2025 | In Use | |||
| Q5160 | Bevacizumab-nwgd (Jobevne) | Jobevne | 10mg | Immunotherapy | Monoclonal Antibody | VEGFR | No | 2025 | Jan 1, 2026 | In Use | ||
| Q5161 | Denosumab-kyqq | Ankelso/Bosaya | 1mg | Immunotherapy | Monoclonal Antibody | RANKL | No | 2025 | Mar 18, 2026 | In Use | ||
| N/A | Zongertinib | HERNEXEOS | 60mg | Chemotherapy | Tyrosine Kinase Inhibitor | HER2 | Yes | 2025 | In Use | |||
| J9183 | Gemcitabine intravesical | Inlexzo | 225mg | Chemotherapy | Antimetabolite | Pyrimidine Analog | No | 2025 | Mar 18, 2026 | In Use | ||
| C9175 | Treosulfan | Grafapex | 50mg | Chemotherapy | Alkylating Agent | Alkyl Sulfonate | No | 2025 | Jul 9, 2025 | Sep 8, 2025 | In Use | |
| J9282 | Mitomycin Intravesical Instillation | Zusduri | 1mg | Chemotherapy | Antitumor Antibiotic | Alkylating Agent/ Mitomycin | No | 2025 | Jan 1, 2026 | In Use | ||
| N/A | Calcium folinate | Lederle Leucovorin | 5mg | Ancillary Therapy | Chemoprotective | Antidote | Yes | 2025 | In Use | |||
| J9011 | Datopotamab Deruxtecan | Datroway | 1mg | Immunotherapy | Drug Antibody Conjugate | Topoisomerase I, TROP2 | No | 2025 | Sep 8, 2025 | In Use |
The use of NA indicates that the HCPCS code was Not Available. NA may mean that a) the HCPCS code has
not yet been created (new drug), b) the drug is given as an oral drug or alternative route (only in
specific instances are HCPCS assigned to these medications), or c) the HCPCS could not be found or is
truly not available.
