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HCPCS Generic Name Brand Name Strength SEER*Rx Category Major Drug Class Minor Drug Class Oral (Y/N) FDA Approval Year FDA Discontinuation Year CMS Effective Date CMS Discontinuation Date Status
C9098 Ciltacabtagene autoleucel CARVYKTI up to 100 million Immunotherapy CAR-T No 2022 Mar 25, 2022 Sep 27, 2022 No Longer Used
S0146 Peginterferon Alfa-2b Pegintron, Sylatron 20 mcg/mL Immunotherapy Cytokine Interferon No 2001 Jul 1, 2005 Sep 30, 2010 No Longer Used
C9260 Ofatumumab Arzerra 10mg Immunotherapy Monoclonal Antibody CD20 No 2009 Apr 1, 2010 Dec 31, 2010 No Longer Used
J9070 Cyclophosphamide Cyclophosphamide 100 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan 1, 1984 Apr 17, 2024 No Longer Used
J9062 Cisplatin Platinol, Platinol-AQ 50 mg Chemotherapy Alkylating Agent Platinum Compound No 1978 Jan 1, 1982 Dec 31, 2010 No Longer Used
C9432 Mitomycin Mitosol 5 mg Chemotherapy Antitumor Antibiotic Alkylating Agent/ Mitomycin No 1981 Jan 1, 2004 Dec 31, 2005 No Longer Used
C9303 Zolbetuximab-clzb Vyloy 1mg Immunotherapy Monoclonal Antibody CLDN18.2 No 2024 Mar 26, 2025 Jul 9, 2025 No Longer Used
J9010 Alemtuzumab Campath 10 mg Immunotherapy Monoclonal Antibody CD52 No 2001 2012 Jan 1, 2003 Dec 31, 2015 No Longer Used
J9093 Cyclophosphamide Cyclophosphamide lyophilized 100 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan 1, 1988 Dec 31, 2010 No Longer Used
C9433 Thiotepa Tepadina 15 mg Chemotherapy Alkylating Agent Nitrogen Mustard /Ethylenimine No 1959 Jan 1, 2004 Dec 31, 2005 No Longer Used
C9210 Palonosetron Aloxi 25 mcg Ancillary Therapy Antiemetic 5HT3 Receptor Antagonist No 2003 Jan 1, 2004 Dec 31, 2004 No Longer Used
J9180 Epirubicin Epirubicin 50 mg Chemotherapy Antitumor Antibiotic Anthracycline No 1999 Jan 1, 2001 Dec 31, 2003 No Longer Used
C9426 Floxuridine Floxuridine 500 mg Chemotherapy Antimetabolite Pyrimidine Analog No 1970 Jan 1, 2004 Dec 31, 2005 No Longer Used
Q2051 Zoledronic acid Zometa (4 mg/5 ml) 1 mg Ancillary Therapy Bisphosphonate No 2001 Jul 1, 2013 Jan 1, 2014 No Longer Used
J9375 Vincristine Oncovin, Vincasar PFS 2 mg Chemotherapy Antimitotic Agent Vinca Alkaloid No 1963 Jan 1, 1988 Dec 31, 2010 No Longer Used
C9427 Ifosfamide ifex 1 g Chemotherapy Alkylating Agent Nitrogen Mustard No 1988 Jan 1, 2004 Dec 31, 2005 No Longer Used
J2930 Methylprednisolone Sodium Succinate A-Methapred, SOLU-medrol 125 mg Hormonal Therapy Adrenal Glucocorticoid Corticosteroid No 1959 Jan 1, 1997 Apr 17, 2024 No Longer Used
J9059 Bendamustine (Baxter) Bendamustine (Baxter) 1mg Chemotherapy Alkylating Agent Nitrogen Mustard No 2022 Jul 11, 2023 Dec 17, 2024 No Longer Used
J1020 Methylprednisolone Acetate DEPO-Medrol, Medrol, Medrol Acetate, SOLU-medrol 20 mg Hormonal Therapy Adrenal Glucocorticoid Corticosteroid No 1959 Jan 1, 1997 Apr 17, 2024 No Longer Used
C9155 Epcoritamab-bysp Epkinly 0.16mg Immunotherapy Monoclonal Antibody CD20, CD3 No 2023 Aug 28, 2023 Dec 7, 2023 No Longer Used
C9302 Zanidatamab-hrii ZIIHERA 2mg Immunotherapy Bispecific Antibody HER2 No 2024 Mar 26, 2025 Jul 9, 2025 No Longer Used
C9292 Pertuzumab Perjeta 10 mg Immunotherapy Monoclonal Antibody HER2 No 2012 Oct 1, 2012 Dec 31, 2013 No Longer Used
C9420 Cyclophosphamide Cyclophosphamide 100 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan 1, 2004 Dec 31, 2005 No Longer Used
C9027 Pembrolizumab Keytruda 1 mg Immunotherapy Checkpoint Inhibitor PD-1 No 2014 Jan 1, 2015 Dec 31, 2015 No Longer Used
C9418 Cisplatin Platinol, Platinol-AQ 10 mg Chemotherapy Alkylating Agent Platinum Compound No 1978 Jan 1, 2004 Dec 31, 2005 No Longer Used
The use of NA indicates that the HCPCS code was Not Available. NA may mean that a) the HCPCS code has not yet been created (new drug), b) the drug is given as an oral drug or alternative route (only in specific instances are HCPCS assigned to these medications), or c) the HCPCS could not be found or is truly not available.