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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
00378-1458-01 00378-1458 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Jun 17, 1999 Jul 31, 2021 No Longer Used
54569-0813-01 54569-0813 Estrogens, Conjugated Premarin 1.25 mg/1 Hormonal Therapy Estrogen Oral Sep 1, 2004 In Use
49999-0109-30 49999-0109 conjugated estrogens Premarin 0.625 mg/1 Hormonal Therapy Estrogen Oral Mar 21, 2012 Jan 1, 2013 In Use
63629-4788-03 63629-4788 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec 22, 2021 In Use
61919-0198-60 61919-0198 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Aug 12, 2019 In Use
51655-0229-26 51655-0229 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb 15, 2023 In Use
55700-0458-90 55700-0458 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov 18, 2016 In Use
68788-8484-06 68788-8484 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jul 13, 2023 In Use
54868-4031-03 54868-4031 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral May 7, 2003 In Use
42806-0089-09 42806-0089 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Apr 10, 2017 In Use
54868-4031-01 54868-4031 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral May 7, 2003 In Use
50090-7480-00 50090-7480 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 20, 2024 In Use
67046-1568-03 67046-1568 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jun 17, 2025 In Use
70934-0927-90 70934-0927 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov 24, 2021 In Use
00046-1102-51 00046-1102 Estrogens, Conjugated Premarin 0.625 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 May 22, 2020 In Use
68788-8860-03 68788-8860 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Apr 11, 2025 In Use
60429-0835-05 60429-0835 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Aug 16, 2016 In Use
50090-1876-00 50090-1876 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Jun 16, 2015 In Use
68071-3202-06 68071-3202 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral May 11, 2017 Dec 31, 2019 No Longer Used
00430-0721-24 00430-0721 Estradiol ESTRACE 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 26, 2011 Aug 31, 2025 In Use
51862-0333-01 51862-0333 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug 3, 2016 May 31, 2023 No Longer Used
21695-0623-30 21695-0623 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 In Use
68788-7892-03 68788-7892 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Apr 23, 2021 May 30, 2023 No Longer Used
10544-0070-30 10544-0070 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 5, 2012 In Use
43063-0201-01 43063-0201 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec 10, 2009 Oct 2, 2017 No Longer Used

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