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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
00378-1452-01 00378-1452 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jun 17, 1999 May 31, 2021 No Longer Used
00378-1454-01 00378-1454 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jun 17, 1999 Jul 31, 2021 No Longer Used
61919-0278-60 61919-0278 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug 12, 2019 In Use
70934-0798-30 70934-0798 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Oct 19, 2020 In Use
68071-3170-09 68071-3170 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 16, 2017 Dec 31, 2019 No Longer Used
54868-4370-01 54868-4370 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jun 9, 2003 In Use
50090-1704-00 50090-1704 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb 18, 2015 In Use
55289-0603-90 55289-0603 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Dec 23, 2009 Nov 23, 2021 No Longer Used
50090-1882-01 50090-1882 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Feb 20, 2019 In Use
61570-0072-01 61570-0072 Esterified Estrogens Menest 0.3 mg/1 Hormonal Therapy Estrogen Oral Sep 28, 1977 Feb 28, 2026 In Use
24658-0703-05 24658-0703 ESTRADIOL ESTRADIOL 1.0 mg/1 Hormonal Therapy Estrogen Oral Sep 10, 2021 In Use
00781-3030-75 00781-3030 Estradiol Valerate Estradiol Valerate Hormonal Therapy Estrogen Oct 4, 2007 Jan 31, 2010 No Longer Used
00179-1999-90 00179-1999 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jul 1, 2008 No Longer Used
24658-0702-05 24658-0702 ESTRADIOL ESTRADIOL 0.5 mg/1 Hormonal Therapy Estrogen Oral Sep 10, 2021 In Use
68788-9901-03 68788-9901 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb 13, 2012 Sep 9, 2019 No Longer Used
54868-4030-01 54868-4030 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Sep 18, 2000 In Use
54868-0365-03 54868-0365 Estrogens, Conjugated Premarin Hormonal Therapy Estrogen Oral Jul 26, 1995 Jun 30, 2012 No Longer Used
00378-1458-77 00378-1458 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Jun 17, 1999 Jul 31, 2021 No Longer Used
55154-0216-06 55154-0216 conjugated estrogens Premarin 0.625 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 Oct 31, 2013 No Longer Used
60429-0327-01 60429-0327 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Nov 26, 2014 Mar 31, 2017 No Longer Used
68788-7892-03 68788-7892 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Apr 23, 2021 May 30, 2023 No Longer Used
66993-0296-02 66993-0296 Estrogens, conjugated Conjugated Estrogens 0.45 mg/1 Hormonal Therapy Estrogen Oral Feb 27, 2026 In Use
00430-0721-24 00430-0721 Estradiol ESTRACE 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 26, 2011 Aug 31, 2025 No Longer Used
69189-0078-01 69189-0078 esterified estrogens Menest 0.625 mg/1 Hormonal Therapy Estrogen Oral Nov 23, 2015 May 24, 2017 No Longer Used
63187-0482-30 63187-0482 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb 2, 2015 Dec 31, 2020 In Use

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