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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
54868-3826-03 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec 5, 2007 In Use
66758-0040-07 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Jun 17, 2010 Mar 31, 2014 No Longer Used
48818-0001-01 48818-0001 Pralatrexate Folotyn 20.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Sep 24, 2009 Jun 30, 2023 No Longer Used
52652-2001-01 52652-2001 Methotrexate Xatmep 2.5 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Oral May 1, 2017 In Use
54868-3826-06 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec 5, 2007 In Use
54868-3826-00 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec 5, 2007 In Use
16729-0522-64 16729-0522 Pemetrexed disodium Pemetrexed 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Sep 8, 2022 Jan 22, 2025 No Longer Used
21695-0111-00 21695-0111 Methotrexate sodium Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Oct 15, 1990 In Use
16729-0522-35 16729-0522 Pemetrexed disodium Pemetrexed 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Sep 8, 2022 Jan 22, 2025 No Longer Used
54868-0173-00 54868-0173 methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Mar 26, 2003 In Use
00409-0021-03 00409-0021 PEMETREXED PEMETREXED 500.0 mg/20mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Feb 1, 2023 In Use
63323-0122-59 63323-0122 Methotrexate Sodium Methotrexate 1.0 g/1 Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Jan 22, 2000 Nov 30, 2017 In Use
62332-0730-31 62332-0730 METHOTREXATE METHOTREXATE 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Jun 4, 2024 In Use
43547-0632-01 43547-0632 Pemetrexed Pemetrexed 100.0 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Intravenous Jul 1, 2024 In Use
63759-3049-01 63759-3049 Pemetrexed disodium Pemetrexed 500.0 mg/50mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Jan 1, 2024 In Use
00054-4550-15 00054-4550 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug 1, 1994 May 31, 2025 In Use
71335-1772-04 71335-1772 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec 29, 2021 In Use
54868-3826-07 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec 5, 2007 In Use
16729-0522-05 16729-0522 Pemetrexed disodium Pemetrexed 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Sep 8, 2022 Feb 28, 2025 No Longer Used
61703-0350-10 61703-0350 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intravenous, Subcutaneous Sep 25, 2014 In Use
16729-0277-35 16729-0277 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Mar 7, 2014 In Use
25021-0261-50 25021-0261 Pemetrexed Disodium Pemetrexed 500.0 mg/20mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Dec 15, 2024 In Use
43598-0370-74 43598-0370 Pemetrexed disodium Pemetrexed disodium 1.0 g/40mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous May 25, 2022 In Use
70771-1058-03 70771-1058 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Feb 9, 2017 In Use
70518-1398-00 70518-1398 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Sep 4, 2018 In Use

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