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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
21695-0623-30 21695-0623 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 In Use
24658-0704-05 24658-0704 ESTRADIOL ESTRADIOL 2.0 mg/1 Hormonal Therapy Estrogen Oral Sep 10, 2021 In Use
68788-8484-09 68788-8484 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jul 13, 2023 In Use
00574-0872-05 00574-0872 Estradiol Valerate Estradiol Valerate 40.0 mg/mL Hormonal Therapy Estrogen Intramuscular Mar 31, 2010 In Use
69189-0886-01 69189-0886 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 14, 2015 May 24, 2017 No Longer Used
00378-1452-05 00378-1452 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jun 17, 1999 Jun 30, 2021 No Longer Used
63629-5208-02 63629-5208 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 In Use
63629-4788-05 63629-4788 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Oct 9, 2017 In Use
00781-3030-75 00781-3030 Estradiol Valerate Estradiol Valerate Hormonal Therapy Estrogen Oct 4, 2007 Jan 31, 2010 No Longer Used
60429-0835-01 60429-0835 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Aug 16, 2016 Oct 31, 2022 In Use
72603-0274-01 72603-0274 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 10, 2024 In Use
63187-0482-60 63187-0482 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb 2, 2015 Dec 31, 2020 In Use
51862-0333-01 51862-0333 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug 3, 2016 May 31, 2023 No Longer Used
55700-0458-30 55700-0458 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov 18, 2016 In Use
00179-1999-88 00179-1999 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Oct 14, 2015 May 31, 2020 No Longer Used
50090-7480-00 50090-7480 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 20, 2024 In Use
42023-0110-01 42023-0110 Estradiol Valerate Delestrogen 10.0 mg/mL Hormonal Therapy Estrogen Intramuscular Nov 1, 2007 In Use
63187-0482-90 63187-0482 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb 2, 2015 Dec 31, 2020 In Use
68788-9416-06 68788-9416 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 4, 2014 Sep 9, 2019 No Longer Used
51862-0334-01 51862-0334 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Aug 3, 2016 Oct 31, 2023 No Longer Used
51655-0860-52 51655-0860 ESTRADIOL ESTRADIOL 0.5 mg/1 Hormonal Therapy Estrogen Oral Feb 9, 2023 In Use
42023-0112-01 42023-0112 Estradiol Valerate Delestrogen 40.0 mg/mL Hormonal Therapy Estrogen Intramuscular Nov 1, 2007 Sep 30, 2024 No Longer Used
67046-1568-03 67046-1568 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jun 17, 2025 In Use
49999-0109-00 49999-0109 conjugated estrogens Premarin 0.625 mg/1 Hormonal Therapy Estrogen Oral Mar 21, 2012 Jan 1, 2013 In Use
00781-3031-75 00781-3031 Estradiol Valerate Estradiol Valerate Hormonal Therapy Estrogen Oct 4, 2007 Aug 31, 2011 No Longer Used

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