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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
70518-2368-02 70518-2368 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Apr 13, 2022 In Use
68788-8484-03 68788-8484 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jul 13, 2023 In Use
00179-1999-70 00179-1999 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jul 1, 2008 No Longer Used
00591-0488-05 00591-0488 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 Dec 31, 2017 In Use
00555-0886-01 00555-0886 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Oct 28, 1997 Jan 26, 2011 In Use
00046-1101-81 00046-1101 Estrogens, Conjugated Premarin 0.45 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 In Use
00046-1100-51 00046-1100 Estrogens, Conjugated Premarin 0.3 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 Apr 30, 2020 In Use
43063-0201-90 43063-0201 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec 10, 2009 Oct 2, 2017 No Longer Used
68788-7961-06 68788-7961 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 16, 2021 In Use
00339-6404-11 00339-6404 Estradiol Estradiol Hormonal Therapy Estrogen Oral Feb 10, 2004 Sep 30, 2011 No Longer Used
68788-8481-03 68788-8481 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jul 13, 2023 In Use
00517-0440-01 00517-0440 ESTRADIOL VALERATE ESTRADIOL VALERATE 40.0 mg/mL Hormonal Therapy Estrogen Intramuscular Mar 1, 2020 In Use
55154-6242-06 55154-6242 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 17, 2009 Sep 30, 2013 No Longer Used
68788-8860-09 68788-8860 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Apr 11, 2025 In Use
00046-1104-91 00046-1104 Estrogens, Conjugated Premarin 1.25 mg/1 Hormonal Therapy Estrogen Oral Sep 1, 2004 In Use
61570-0072-01 61570-0072 Esterified Estrogens Menest 0.3 mg/1 Hormonal Therapy Estrogen Oral Sep 28, 1977 In Use
68788-7332-03 68788-7332 ESTRADIOL ESTRADIOL 0.5 mg/1 Hormonal Therapy Estrogen Oral Mar 12, 2019 In Use
55289-0761-01 55289-0761 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 21, 2009 Nov 23, 2021 No Longer Used
00430-0722-24 00430-0722 Estradiol ESTRACE 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec 26, 2011 Aug 31, 2025 In Use
55289-0761-90 55289-0761 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 21, 2009 Nov 23, 2021 No Longer Used
42023-0136-01 42023-0136 Estradiol Valerate Estradiol Valerate 40.0 mg/mL Hormonal Therapy Estrogen Intramuscular Jun 1, 2012 Mar 31, 2017 No Longer Used
71335-2477-05 71335-2477 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Sep 3, 2024 In Use
50268-0291-11 50268-0291 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Sep 30, 2014 Mar 19, 2018 No Longer Used
50090-1343-00 50090-1343 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Nov 28, 2014 In Use
72189-0183-60 72189-0183 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb 24, 2021 In Use

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