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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
50242-0717-01 50242-0717 Cobimetinib Cotellic 20.0 mg/1 Chemotherapy MAPK/MEK Inhibitor BRAF Oral Nov 10, 2015 In Use
71779-0623-01 71779-0623 Avutometinib potassium and defactinib hydrochloride AVMAPKI FAKZYNJA CO-PACK 0.8 mg/1, 200.0 mg/1 Chemotherapy MEK Inhibitor, Tyrosine Kinase Inhibitor MEK1/2, ERK1/2, KRAS, FAK Oral May 8, 2025 In Use
00173-0848-13 00173-0848 Trametinib Mekinist 2.0 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Jun 17, 2013 Dec 31, 2016 No Longer Used
00078-0668-15 00078-0668 Trametinib Mekinist 2.0 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Mar 17, 2016 Apr 30, 2024 No Longer Used
00310-0610-60 00310-0610 SELUMETINIB KOSELUGO 10.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Apr 16, 2020 In Use
00173-0858-13 00173-0858 Trametinib Mekinist 1.0 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Jun 17, 2013 Oct 5, 2015 No Longer Used
70255-0010-03 70255-0010 BINIMETINIB MEKTOVI 15.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Jun 27, 2018 In Use
00078-0666-15 00078-0666 Trametinib Mekinist 0.5 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Mar 17, 2016 Oct 31, 2023 No Longer Used
00173-0848-65 00173-0848 Trametinib Mekinist 2.0 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Jun 17, 2013 Nov 30, 2016 No Longer Used
00078-1161-47 00078-1161 Trametinib Mekinist 0.05 mg/mL Chemotherapy MEK Inhibitor BRAF Oral Mar 16, 2023 In Use
00173-0849-13 00173-0849 Trametinib Mekinist 0.5 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Jun 17, 2013 Dec 31, 2016 No Longer Used
70255-0010-02 70255-0010 BINIMETINIB MEKTOVI 15.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Jun 27, 2018 In Use
00310-0625-60 00310-0625 SELUMETINIB KOSELUGO 25.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Apr 16, 2020 In Use
00310-0625-28 00310-0625 SELUMETINIB KOSELUGO 25.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Jun 11, 2021 In Use
00310-0610-28 00310-0610 SELUMETINIB KOSELUGO 10.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Jun 11, 2021 In Use
00024-5151-75 00024-5151 Rasburicase Elitek Ancillary Therapy Metabolic Agent Enzyme Jun 1, 2006 In Use
00024-5150-10 00024-5150 Rasburicase Elitek Ancillary Therapy Metabolic Agent Enzyme Jul 12, 2002 In Use
81607-0005-11 81607-0005 Arsenic trioxide ARSENIC TRIOXIDE 1.0 mg/mL Chemotherapy Miscellaneous Agent PML/RARa Intravenous May 31, 2023 In Use
00574-0792-01 00574-0792 pilocarpine hydrchloride pilocarpine hydrchloride 5.0 mg/1 Ancillary Therapy Miscellaneous Agent Cholinergic Agonist Oral Aug 24, 2020 Jan 31, 2026 In Use
70710-1895-06 70710-1895 Arsenic trioxide Arsenic trioxide 1.0 mg/mL Chemotherapy Miscellaneous Agent PML/RARa Intravenous Feb 28, 2023 In Use
00006-5331-59 00006-5331 Belzutifan WELIREG 40.0 mg/1 Chemotherapy Miscellaneous Agent HIF-2 alpha Oral Jun 21, 2023 In Use
00555-0882-02 00555-0882 Hydroxyurea Hydroxyurea 500.0 mg/1 Chemotherapy Miscellaneous Agent Antimetabolite/Organooxygen Oral Oct 19, 1998 In Use
72694-0954-01 72694-0954 Pegaspargase Oncaspar 750.0 [iU]/mL Chemotherapy Miscellaneous Agent Enzyme Intramuscular, Intravenous Jan 2, 2020 In Use
00006-5331-58 00006-5331 Belzutifan WELIREG 40.0 mg/1 Chemotherapy Miscellaneous Agent HIF-2 alpha Oral Jun 21, 2023 In Use
70518-0916-00 70518-0916 Hydroxyurea Hydroxyurea 500.0 mg/1 Chemotherapy Miscellaneous Agent Antimetabolite/Organooxygen Oral Dec 20, 2017 In Use

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