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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
63629-5208-01 63629-5208 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 In Use
00574-0870-05 00574-0870 Estradiol Valerate Estradiol Valerate 20.0 mg/mL Hormonal Therapy Estrogen Intramuscular Mar 31, 2010 In Use
00430-0722-24 00430-0722 Estradiol ESTRACE 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec 26, 2011 Aug 31, 2025 No Longer Used
51862-0332-01 51862-0332 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Aug 3, 2016 May 31, 2023 No Longer Used
50742-0387-01 50742-0387 Estrogens, conjugated Estrogens, conjugated 0.3 mg/1 Hormonal Therapy Estrogen Oral Oct 16, 2025 In Use
54868-4370-01 54868-4370 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jun 9, 2003 In Use
69189-0899-01 69189-0899 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Oct 29, 2015 May 24, 2017 No Longer Used
63629-3755-01 63629-3755 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 Mar 30, 2018 No Longer Used
54868-4031-01 54868-4031 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral May 7, 2003 In Use
50742-0391-01 50742-0391 Estrogens, conjugated Estrogens, conjugated 1.25 mg/1 Hormonal Therapy Estrogen Oral Oct 16, 2025 In Use
54348-0701-30 54348-0701 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 9, 2019 In Use
71335-2387-02 71335-2387 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 8, 2024 In Use
61570-0073-01 61570-0073 Esterified Estrogens Menest 0.625 mg/1 Hormonal Therapy Estrogen Oral Sep 28, 1977 Feb 28, 2026 In Use
00046-1104-91 00046-1104 Estrogens, Conjugated Premarin 1.25 mg/1 Hormonal Therapy Estrogen Oral Sep 1, 2004 In Use
21695-0623-00 21695-0623 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 In Use
50090-1941-00 50090-1941 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb 9, 2017 Feb 9, 2017 No Longer Used
00591-0488-01 00591-0488 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 Jun 30, 2018 In Use
68788-9416-06 68788-9416 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 4, 2014 Sep 9, 2019 No Longer Used
61570-0181-01 61570-0181 Estradiol Valerate Delestrogen Hormonal Therapy Estrogen Jul 15, 1954 Oct 1, 2007 No Longer Used
68788-7102-01 68788-7102 ESTRADIOL ESTRADIOL 1.0 mg/1 Hormonal Therapy Estrogen Oral Mar 12, 2018 In Use
68788-8481-06 68788-8481 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jul 13, 2023 In Use
63629-3755-05 63629-3755 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov 24, 2008 Mar 30, 2018 No Longer Used
55289-0603-30 55289-0603 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Dec 23, 2009 Nov 23, 2021 No Longer Used
00046-1102-51 00046-1102 Estrogens, Conjugated Premarin 0.625 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 May 22, 2020 In Use
61919-0198-60 61919-0198 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Aug 12, 2019 In Use

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