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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
68682-0085-31 68682-0085 Fluorouracil Fluorouracil Chemotherapy Antimetabolite Pyrimidine Analog Topical Sep 30, 1990 Jan 31, 2010 No Longer Used
75907-0169-11 75907-0169 Fluorouracil Cream, 0.5% FLUOROURACIL 5.0 mg/g Chemotherapy Antimetabolite Pyrimidine Analog Topical Jul 6, 2025 In Use
60505-6067-00 60505-6067 Pemetrexed disodium Pemetrexed 1000.0 mg/40mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous May 25, 2022 In Use
69097-0368-40 69097-0368 Azacitidine Azacitidine 100.0 mg/1 Chemotherapy Antimetabolite Pyrimidine Analog Intravenous, Subcutaneous May 4, 2018 In Use
57665-0331-01 57665-0331 Cytarabine DepoCyt 50.0 mg/5mL Chemotherapy Antimetabolite Pyrimidine Analog Intrathecal Oct 22, 2010 Jun 30, 2018 No Longer Used
71288-0146-50 71288-0146 Pemetrexed disodium Pemetrexed 500.0 mg/20mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Dec 13, 2022 In Use
68001-0525-32 68001-0525 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Feb 18, 2022 In Use
45963-0619-59 45963-0619 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 1.0 g/25mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Feb 2, 2015 Jul 31, 2021 No Longer Used
00069-0173-01 00069-0173 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Jul 18, 2012 Nov 30, 2014 No Longer Used
00069-0181-01 00069-0181 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Mar 30, 2012 Dec 31, 2017 No Longer Used
51991-0797-98 51991-0797 Azacitidine Azacitidine 100.0 mg/50mL Chemotherapy Antimetabolite Pyrimidine Analog Subcutaneous Aug 7, 2017 Jan 31, 2024 No Longer Used
00054-4581-27 00054-4581 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Feb 13, 2004 In Use
25021-0231-20 25021-0231 Decitabine Decitabine 50.0 mg/10mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Aug 15, 2018 Nov 30, 2024 No Longer Used
52549-4118-05 52549-4118 Fluorouracil Fluorouracil 50.0 mg/g Chemotherapy Antimetabolite Pyrimidine Analog Topical Mar 5, 2010 In Use
82511-0002-50 82511-0002 Capecitabine Capecitabine 500.0 mg/1 Chemotherapy Antimetabolite Pyrimidine Analog Oral Feb 16, 2022 In Use
68382-0775-77 68382-0775 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Feb 9, 2017 In Use
00143-9518-01 00143-9518 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-Arterial, Intramuscular, Intrathecal, Intravenous Jan 5, 2018 In Use
71335-2221-03 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug 15, 2023 In Use
54868-5260-01 54868-5260 Capecitabine Xeloda 500.0 mg/1 Chemotherapy Antimetabolite Pyrimidine Analog Oral Jun 28, 2005 In Use
00409-0185-01 00409-0185 GEMCITABINE Gemcitabine 38.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Jul 26, 2011 In Use
59572-0102-01 59572-0102 Azacitidine Vidaza 100.0 mg/1 Chemotherapy Antimetabolite Pyrimidine Analog Intravenous, Subcutaneous Jul 5, 2004 In Use
59148-0046-70 59148-0046 Decitabine Dacogen 50.0 mg/20mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous May 2, 2006 Apr 15, 2024 No Longer Used
43598-0343-23 43598-0343 Pralatrexate Pralatrexate 40.0 mg/2mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Nov 1, 2025 In Use
55390-0032-10 55390-0032 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous May 1, 1996 Oct 31, 2012 No Longer Used
61703-0344-18 61703-0344 Fludarabine Phosphate Fludarabine Phosphate 50.0 mg/2mL Chemotherapy Antimetabolite Purine Analog Intravenous Sep 25, 2008 Sep 30, 2021 No Longer Used

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