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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
00591-0528-01 00591-0528 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 Dec 31, 2017 In Use
42806-0089-01 42806-0089 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Apr 10, 2017 In Use
68788-8626-06 68788-8626 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Apr 9, 2024 In Use
00046-1100-51 00046-1100 Estrogens, Conjugated Premarin 0.3 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 Apr 30, 2020 In Use
43063-0706-90 43063-0706 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Sep 20, 2016 Oct 31, 2023 No Longer Used
54868-4030-01 54868-4030 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Sep 18, 2000 In Use
68071-3202-09 68071-3202 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral May 11, 2017 Dec 31, 2019 No Longer Used
54868-4370-00 54868-4370 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jun 9, 2003 In Use
66267-0093-60 66267-0093 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Oct 28, 1997 Dec 13, 2018 No Longer Used
00143-9289-01 00143-9289 Estradiol Valerate Estradiol Valerate 10.0 mg/mL Hormonal Therapy Estrogen Intramuscular Apr 21, 2020 In Use
50268-0291-15 50268-0291 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 12, 2014 Mar 19, 2018 No Longer Used
55289-0603-21 55289-0603 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Dec 23, 2009 Nov 23, 2021 No Longer Used
63629-3755-05 63629-3755 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov 24, 2008 Mar 30, 2018 No Longer Used
72603-0274-02 72603-0274 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 10, 2024 In Use
00378-1458-77 00378-1458 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Jun 17, 1999 Jul 31, 2021 No Longer Used
49999-0083-30 49999-0083 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Mar 12, 2012 Nov 18, 2016 No Longer Used
50090-0666-00 50090-0666 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov 28, 2014 May 31, 2017 No Longer Used
60429-0833-01 60429-0833 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Aug 16, 2016 Dec 31, 2022 No Longer Used
69189-0487-01 69189-0487 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jun 23, 2015 May 24, 2017 No Longer Used
68788-9416-09 68788-9416 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 4, 2014 Sep 9, 2019 No Longer Used
00430-0721-24 00430-0721 Estradiol ESTRACE 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 26, 2011 Aug 31, 2025 No Longer Used
00046-1101-81 00046-1101 Estrogens, Conjugated Premarin 0.45 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 In Use
00430-0722-24 00430-0722 Estradiol ESTRACE 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec 26, 2011 Aug 31, 2025 No Longer Used
50090-1853-03 50090-1853 Estrogens, Conjugated Premarin 0.3 mg/1 Hormonal Therapy Estrogen Oral Jun 2, 2015 In Use
68788-8063-09 68788-8063 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug 16, 2021 Oct 30, 2023 No Longer Used

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