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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
61786-0417-02 61786-0417 Methotrexate sodium Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Sep 23, 2015 Jan 24, 2017 No Longer Used
83831-0132-01 83831-0132 Pemetrexed AXTLE 500.0 mg/20mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Jan 1, 2025 In Use
66758-0040-01 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Jun 17, 2010 Mar 31, 2014 No Longer Used
72603-0325-01 72603-0325 Pemetrexed disodium Pemetrexed 100.0 mg/10mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Oct 1, 2024 In Use
00480-4515-01 00480-4515 Pemetrexed Pemetrexed 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous May 31, 2022 In Use
71335-2221-08 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug 15, 2023 In Use
69238-1423-06 69238-1423 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec 29, 2017 In Use
66758-0040-02 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Jun 1, 2009 Mar 31, 2014 No Longer Used
61703-0408-22 61703-0408 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous, Subcutaneous Feb 26, 2001 Nov 2, 2011 In Use
70121-1232-01 70121-1232 Pemetrexed Pemetrexed disodium 100.0 mg/10mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous May 16, 2023 In Use
47781-0482-01 47781-0482 Methotrexate METHOTREXATE 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Apr 27, 2022 Nov 1, 2023 In Use
61703-0408-41 61703-0408 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous, Subcutaneous Feb 26, 2001 In Use
68001-0537-41 68001-0537 Pemetrexed Pemetrexed 1000.0 mg/40mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Jul 4, 2022 Jul 5, 2022 No Longer Used
71335-2221-02 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug 15, 2023 In Use
51285-0367-01 51285-0367 Methotrexate Trexall 7.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral May 3, 2001 In Use
16729-0277-30 16729-0277 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Mar 7, 2014 In Use
68071-3765-09 68071-3765 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Jan 10, 2025 In Use
54868-3826-04 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec 5, 2007 In Use
70771-1058-02 70771-1058 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Feb 9, 2017 In Use
71335-2221-04 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug 15, 2023 In Use
21695-0111-00 21695-0111 Methotrexate sodium Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Oct 15, 1990 In Use
71335-2221-06 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug 15, 2023 In Use
25021-0260-10 25021-0260 Pemetrexed Disodium Pemetrexed 100.0 mg/4.2mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Dec 15, 2024 In Use
00069-0181-02 00069-0181 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Mar 30, 2012 Dec 31, 2017 No Longer Used
55390-0033-10 55390-0033 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog May 1, 1996 Oct 31, 2012 No Longer Used

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