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NDC-11 (Package) NDC-9 (Product) Generic Name (Ascending) Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
60429-0835-01 60429-0835 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 16, 2016 Oct. 31, 2022 In Use
60429-0835-05 60429-0835 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 16, 2016 In Use
60429-0833-01 60429-0833 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Aug. 16, 2016 Dec. 31, 2022 No Longer Used
68071-3394-02 68071-3394 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral July 12, 2017 In Use
68071-3394-03 68071-3394 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral July 12, 2017 In Use
68071-3394-06 68071-3394 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral July 12, 2017 In Use
68071-3394-09 68071-3394 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral July 12, 2017 In Use
70518-2595-00 70518-2595 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Feb. 25, 2020 In Use
70934-0215-30 70934-0215 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 28, 2018 In Use
70934-0215-90 70934-0215 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral May 19, 2020 In Use
70934-0393-30 70934-0393 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral June 13, 2019 In Use
70934-0506-30 70934-0506 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral March 19, 2020 In Use
70934-0506-90 70934-0506 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral March 17, 2021 In Use
70934-0541-30 70934-0541 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb. 4, 2020 In Use
70934-0541-90 70934-0541 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral July 29, 2020 In Use
70934-0786-90 70934-0786 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral July 30, 2020 In Use
70934-0798-30 70934-0798 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Oct. 19, 2020 In Use
51655-0229-26 51655-0229 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb. 15, 2023 In Use
51655-0229-52 51655-0229 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral March 17, 2023 In Use
70518-2368-00 70518-2368 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Oct. 19, 2019 In Use
70518-2368-02 70518-2368 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral April 13, 2022 In Use
50090-1876-00 50090-1876 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral June 16, 2015 In Use
50090-1876-02 50090-1876 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral June 12, 2018 In Use
50090-1882-00 50090-1882 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral June 16, 2015 In Use
50090-1882-01 50090-1882 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Feb. 20, 2019 In Use
63629-4788-01 63629-4788 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 22, 2021 In Use
63629-4788-02 63629-4788 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 22, 2021 In Use
63629-4788-03 63629-4788 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 22, 2021 In Use
63629-4788-04 63629-4788 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 22, 2021 In Use
63629-4788-05 63629-4788 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Oct. 9, 2017 In Use
00430-0720-24 00430-0720 Estradiol ESTRACE 0.5 mg/1 Hormonal Therapy Estrogen Oral Dec. 26, 2011 Aug. 31, 2025 In Use
00430-0721-24 00430-0721 Estradiol ESTRACE 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 26, 2011 Aug. 31, 2025 In Use
00430-0722-24 00430-0722 Estradiol ESTRACE 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 26, 2011 Aug. 31, 2025 In Use
72189-0508-90 72189-0508 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 17, 2023 In Use
51862-0332-01 51862-0332 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Aug. 3, 2016 May 31, 2023 No Longer Used
61919-0278-30 61919-0278 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jan. 1, 2015 Nov. 6, 2017 In Use
61919-0278-60 61919-0278 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 12, 2019 In Use
68788-7892-01 68788-7892 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral April 23, 2021 May 30, 2023 No Longer Used
68788-7892-03 68788-7892 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral April 23, 2021 May 30, 2023 No Longer Used
68788-7892-06 68788-7892 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral April 23, 2021 May 30, 2023 No Longer Used
68788-7892-09 68788-7892 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral April 23, 2021 May 30, 2023 No Longer Used
70934-0927-30 70934-0927 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov. 24, 2021 In Use
70934-0927-90 70934-0927 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov. 24, 2021 In Use
70518-3910-00 70518-3910 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Nov. 7, 2023 In Use
70518-3910-02 70518-3910 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Nov. 10, 2023 In Use
70518-3922-00 70518-3922 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov. 22, 2023 In Use
43063-0706-30 43063-0706 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Oct. 6, 2016 Oct. 31, 2023 No Longer Used
43063-0706-90 43063-0706 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Sept. 20, 2016 Oct. 31, 2023 No Longer Used
43063-0717-30 43063-0717 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Sept. 21, 2017 Oct. 31, 2023 No Longer Used
43063-0717-90 43063-0717 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Oct. 12, 2016 Oct. 31, 2023 No Longer Used
51862-0333-01 51862-0333 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 3, 2016 May 31, 2023 No Longer Used
51862-0333-05 51862-0333 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 3, 2016 Oct. 31, 2023 No Longer Used
51862-0334-01 51862-0334 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 3, 2016 Oct. 31, 2023 No Longer Used
51862-0334-05 51862-0334 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 3, 2016 Nov. 30, 2023 No Longer Used
68788-8063-01 68788-8063 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 16, 2021 Oct. 30, 2023 No Longer Used
68788-8063-03 68788-8063 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 16, 2021 Oct. 30, 2023 No Longer Used
68788-8063-06 68788-8063 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 16, 2021 Oct. 30, 2023 No Longer Used
68788-8063-09 68788-8063 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug. 16, 2021 Oct. 30, 2023 No Longer Used
51655-0227-26 51655-0227 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Feb. 15, 2023 In Use
51655-0227-52 51655-0227 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral June 28, 2023 In Use
68788-8481-01 68788-8481 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral July 13, 2023 In Use
68788-8481-03 68788-8481 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral July 13, 2023 In Use
68788-8481-06 68788-8481 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral July 13, 2023 In Use
68788-8481-09 68788-8481 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral July 13, 2023 In Use
68788-8484-01 68788-8484 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral July 13, 2023 In Use
68788-8484-03 68788-8484 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral July 13, 2023 In Use
68788-8484-06 68788-8484 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral July 13, 2023 In Use
68788-8484-09 68788-8484 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral July 13, 2023 In Use
70518-2369-00 70518-2369 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Oct. 19, 2019 In Use
70518-2369-02 70518-2369 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral May 25, 2023 In Use
70954-0565-10 70954-0565 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Sept. 6, 2023 In Use
70954-0565-20 70954-0565 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Sept. 6, 2023 In Use
70954-0566-10 70954-0566 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Sept. 6, 2023 In Use
70954-0566-20 70954-0566 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Sept. 6, 2023 In Use
70954-0564-10 70954-0564 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Sept. 6, 2023 In Use
82868-0026-30 82868-0026 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Nov. 9, 2023 In Use
82868-0038-30 82868-0038 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb. 5, 2024 In Use
82868-0038-90 82868-0038 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jan. 18, 2024 In Use
00143-9289-01 00143-9289 Estradiol Valerate Estradiol Valerate 10.0 mg/mL Hormonal Therapy Estrogen Intramuscular April 21, 2020 In Use
00143-9290-01 00143-9290 Estradiol Valerate Estradiol Valerate 20.0 mg/mL Hormonal Therapy Estrogen Intramuscular April 21, 2020 In Use
00143-9291-01 00143-9291 Estradiol Valerate Estradiol Valerate 40.0 mg/mL Hormonal Therapy Estrogen Intramuscular April 21, 2020 In Use
00781-3029-75 00781-3029 Estradiol Valerate Estradiol Valerate Hormonal Therapy Estrogen Oct. 4, 2007 Dec. 31, 2011 No Longer Used
00781-3030-75 00781-3030 Estradiol Valerate Estradiol Valerate Hormonal Therapy Estrogen Oct. 4, 2007 Jan. 31, 2010 No Longer Used
00781-3031-75 00781-3031 Estradiol Valerate Estradiol Valerate Hormonal Therapy Estrogen Oct. 4, 2007 Aug. 31, 2011 No Longer Used
42023-0110-01 42023-0110 Estradiol Valerate Delestrogen 10.0 mg/mL Hormonal Therapy Estrogen Intramuscular Nov. 1, 2007 In Use
42023-0111-01 42023-0111 Estradiol Valerate Delestrogen 20.0 mg/mL Hormonal Therapy Estrogen Intramuscular Nov. 1, 2007 In Use
42023-0112-01 42023-0112 Estradiol Valerate Delestrogen 40.0 mg/mL Hormonal Therapy Estrogen Intramuscular Nov. 1, 2007 In Use
61570-0180-01 61570-0180 Estradiol Valerate Delestrogen Hormonal Therapy Estrogen July 15, 1954 Oct. 1, 2007 No Longer Used
61570-0181-01 61570-0181 Estradiol Valerate Delestrogen Hormonal Therapy Estrogen July 15, 1954 Oct. 1, 2007 No Longer Used
61570-0182-01 61570-0182 Estradiol Valerate Delestrogen Hormonal Therapy Estrogen July 15, 1954 Oct. 1, 2007 No Longer Used
42023-0134-01 42023-0134 Estradiol Valerate Estradiol Valerate 10.0 mg/mL Hormonal Therapy Estrogen Intramuscular June 1, 2012 Feb. 28, 2016 No Longer Used
42023-0135-01 42023-0135 Estradiol Valerate Estradiol Valerate 20.0 mg/mL Hormonal Therapy Estrogen Intramuscular June 1, 2012 March 31, 2017 No Longer Used
42023-0136-01 42023-0136 Estradiol Valerate Estradiol Valerate 40.0 mg/mL Hormonal Therapy Estrogen Intramuscular June 1, 2012 March 31, 2017 No Longer Used
00574-0870-05 00574-0870 Estradiol Valerate Estradiol Valerate 20.0 mg/mL Hormonal Therapy Estrogen Intramuscular March 31, 2010 In Use
00574-0872-05 00574-0872 Estradiol Valerate Estradiol Valerate 40.0 mg/mL Hormonal Therapy Estrogen Intramuscular March 31, 2010 In Use
57377-0025-01 57377-0025 Estradiol pellet Estra-25 25.0 mg/1 Hormonal Therapy Estrogen Subcutaneous Jan. 1, 2017 In Use
57377-0050-01 57377-0050 Estradiol pellet Estra-50 50.0 mg/1 Hormonal Therapy Estrogen Subcutaneous Jan. 1, 2017 In Use
00013-0132-02 00013-0132 Estramustine Phosphate Sodium Emcyt 140.0 mg/1 Chemotherapy Alkylating Agent Nitrogen Mustard Oral Jan. 1, 1992 Sept. 30, 2024 In Use
00046-1101-81 00046-1101 Estrogens, Conjugated Premarin 0.45 mg/1 Hormonal Therapy Estrogen Oral Jan. 1, 2006 In Use
00046-1103-81 00046-1103 Estrogens, Conjugated Premarin 0.9 mg/1 Hormonal Therapy Estrogen Oral Jan. 1, 2006 In Use

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