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NDC-11 (Package) NDC-9 (Product) Generic Name (Descending) Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
71335-2221-01 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 15, 2023 In Use
71335-2221-02 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 15, 2023 In Use
71335-2221-03 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 15, 2023 In Use
71335-2221-04 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 15, 2023 In Use
71335-2221-05 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 15, 2023 In Use
71335-2221-06 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 15, 2023 In Use
71335-2221-07 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 15, 2023 In Use
71335-2221-08 71335-2221 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 15, 2023 In Use
47781-0482-01 47781-0482 Methotrexate METHOTREXATE 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral April 27, 2022 Nov. 1, 2023 In Use
50268-0527-15 50268-0527 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral May 26, 2021 In Use
51079-0670-01 51079-0670 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral July 13, 1995 In Use
51079-0670-05 51079-0670 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral July 13, 1995 In Use
81927-0204-01 81927-0204 Methotrexate JYLAMVO 2.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 15, 2023 In Use
68083-0161-10 68083-0161 Mesna Injection Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Dec. 20, 2017 In Use
68083-0161-01 68083-0161 Mesna Injection Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Dec. 20, 2017 In Use
55390-0045-01 55390-0045 Mesna Mesna Ancillary Therapy Chemoprotective Detoxifying Agent Feb. 23, 2004 July 31, 2012 No Longer Used
55390-0266-01 55390-0266 Mesna Mesna Ancillary Therapy Chemoprotective Detoxifying Agent Jan. 9, 2004 July 31, 2012 No Longer Used
55390-0347-01 55390-0347 Mesna Mesna Ancillary Therapy Chemoprotective Detoxifying Agent March 3, 2008 July 31, 2012 No Longer Used
63323-0733-10 63323-0733 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Sept. 5, 2001 In Use
63323-0733-11 63323-0733 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Sept. 5, 2001 In Use
10019-0953-01 10019-0953 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Dec. 30, 1988 In Use
10019-0953-02 10019-0953 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Dec. 30, 1988 In Use
10019-0953-62 10019-0953 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Dec. 30, 1988 In Use
25021-0201-10 25021-0201 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Dec. 1, 2010 In Use
25021-0201-11 25021-0201 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Dec. 1, 2010 In Use
25021-0201-66 25021-0201 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous April 30, 2013 Aug. 31, 2016 In Use
25021-0201-67 25021-0201 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous April 30, 2013 Sept. 30, 2016 In Use
25021-0201-68 25021-0201 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous April 30, 2013 Sept. 13, 2019 In Use
25021-0201-69 25021-0201 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous April 30, 2013 Sept. 13, 2019 In Use
00338-1305-01 00338-1305 Mesna Mesnex 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Dec. 30, 1988 In Use
00338-1305-03 00338-1305 Mesna Mesnex 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Dec. 30, 1988 In Use
67457-0148-00 67457-0148 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous April 3, 2012 Sept. 30, 2016 No Longer Used
67457-0148-10 67457-0148 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous April 3, 2012 Sept. 30, 2016 No Longer Used
76126-0075-01 76126-0075 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous July 19, 2014 Sept. 1, 2017 No Longer Used
00703-4805-01 00703-4805 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous May 1, 2002 Oct. 31, 2020 No Longer Used
00703-4805-03 00703-4805 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous May 1, 2002 Jan. 31, 2013 No Longer Used
67108-3565-09 67108-3565 Mesna Mesnex 400.0 mg/1 Ancillary Therapy Chemoprotective Detoxifying Agent Oral March 21, 2002 In Use
47781-0622-22 47781-0622 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous March 29, 2018 March 1, 2020 In Use
47781-0622-91 47781-0622 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous March 29, 2018 March 1, 2020 In Use
70860-0209-10 70860-0209 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Feb. 28, 2018 In Use
70860-0209-11 70860-0209 Mesna Mesna 100.0 mg/mL Ancillary Therapy Chemoprotective Detoxifying Agent Intravenous Feb. 28, 2018 In Use
49884-0922-02 49884-0922 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Feb. 11, 2004 April 30, 2018 No Longer Used
49884-0922-04 49884-0922 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Feb. 11, 2004 April 30, 2018 No Longer Used
49884-0922-15 49884-0922 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Feb. 11, 2004 Jan. 20, 2010 No Longer Used
69189-4581-01 69189-4581 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral March 1, 2015 May 24, 2017 No Longer Used
68084-0325-01 68084-0325 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral March 19, 2013 Sept. 30, 2015 No Longer Used
68084-0325-11 68084-0325 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Dec. 16, 2009 March 19, 2013 No Longer Used
68084-0325-21 68084-0325 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Dec. 16, 2009 Sept. 30, 2015 No Longer Used
00054-4581-11 00054-4581 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Feb. 13, 2004 In Use
00054-4581-27 00054-4581 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Feb. 13, 2004 In Use
00093-5510-06 00093-5510 Mercaptopurine Mercaptopurine Chemotherapy Antimetabolite Purine Analog Oral April 27, 2005 Oct. 31, 2013 No Longer Used
49349-0606-16 49349-0606 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Nov. 3, 2011 Nov. 3, 2012 No Longer Used
54868-5282-00 54868-5282 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral May 23, 2005 In Use
54868-5282-01 54868-5282 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral May 23, 2005 In Use
54868-5282-02 54868-5282 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral May 23, 2005 In Use
69076-0913-02 69076-0913 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Oct. 5, 2016 In Use
69076-0913-25 69076-0913 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Oct. 5, 2016 In Use
60763-0601-13 60763-0601 Mercaptopurine PURINETHOL 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Jan. 15, 2022 In Use
00378-3547-25 00378-3547 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral July 1, 2005 June 30, 2025 In Use
00378-3547-52 00378-3547 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral July 1, 2005 In Use
75833-0601-01 75833-0601 Melphalan hydrochloride injection, powder, lyophilized, for solution Hepzato Kit Chemotherapy Alkylating Agent Nitrogen Mustard Intra-arterial Dec. 4, 2023 In Use
75833-0601-02 75833-0601 Melphalan hydrochloride injection, powder, lyophilized, for solution Hepzato Kit Chemotherapy Alkylating Agent Nitrogen Mustard Intra-arterial Dec. 4, 2023 In Use
75833-0601-07 75833-0601 Melphalan hydrochloride injection, powder, lyophilized, for solution Hepzato Kit Chemotherapy Alkylating Agent Nitrogen Mustard Intra-arterial Dec. 4, 2023 In Use
75833-0601-08 75833-0601 Melphalan hydrochloride injection, powder, lyophilized, for solution Hepzato Kit Chemotherapy Alkylating Agent Nitrogen Mustard Intra-arterial Dec. 4, 2023 In Use
71288-0132-90 71288-0132 Melphalan hydrochloride Melphalan hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous May 28, 2021 In Use
68083-0259-01 68083-0259 Melphalan hydrochloride Melphalan hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous June 10, 2019 In Use
71288-0112-90 71288-0112 Melphalan hydrochloride Melphalan hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous June 30, 2019 April 30, 2025 In Use
70700-0278-97 70700-0278 Melphalan hydrochloride Melphalan hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Jan. 6, 2021 In Use
72266-0128-01 72266-0128 Melphalan hydrochloride Melphalan hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Sept. 23, 2019 In Use
72611-0779-02 72611-0779 Melphalan hydrochloride Melphalan hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Nov. 1, 2020 In Use
70860-0228-61 70860-0228 Melphalan hydrochloride Melphalan Hydrochloride 50.0 mg/10mL Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Sept. 1, 2023 In Use
83634-0202-61 83634-0202 Melphalan hydrochloride Melphalan Hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Dec. 18, 2023 In Use
70860-0214-61 70860-0214 Melphalan hydrochloride Melphalan hydrochloride 50.0 mg/10ml Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous July 30, 2019 Oct. 31, 2025 In Use
47781-0200-50 47781-0200 Melphalan USP, 2 mg Melphalan 2.0 mg/1 Chemotherapy Alkylating Agent Nitrogen Mustard Oral March 22, 2017 May 1, 2024 In Use
42023-0149-01 42023-0149 Melphalan Hydrochloride Melphalan Hydrochloride 50.0 mg/10mL Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Aug. 26, 2016 April 30, 2019 In Use
25021-0221-60 25021-0221 Melphalan Hydrochloride Melphalan Hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous March 15, 2017 April 30, 2020 No Longer Used
43598-0392-48 43598-0392 Melphalan Hydrochloride Melphalan Hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Dec. 18, 2017 In Use
45963-0686-02 45963-0686 Melphalan Hydrochloride Melphalan Hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Jan. 13, 2017 In Use
43598-0027-48 43598-0027 Melphalan Hydrochloride Melphalan Hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous April 26, 2021 In Use
54288-0109-02 54288-0109 Melphalan Hydrochloride Melphalan hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard July 2, 2021 In Use
00173-0130-93 00173-0130 Melphalan Hydrochloride Alkeran Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous March 16, 1993 May 31, 2012 No Longer Used
52609-3001-00 52609-3001 Melphalan Hydrochloride Alkeran Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Jan. 1, 2011 In Use
54288-0106-03 54288-0106 Melphalan Hydrochloride Melphalan Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Sept. 30, 2020 In Use
59572-0301-01 59572-0301 Melphalan Hydrochloride Alkeran Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous March 16, 1993 Nov. 2, 2009 No Longer Used
63323-0760-20 63323-0760 Melphalan Hydrochloride Melphalan Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Dec. 22, 2017 In Use
67457-0195-01 67457-0195 Melphalan Hydrochloride Melphalan Hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Jan. 10, 2013 In Use
67457-0215-01 67457-0215 Melphalan Hydrochloride Melphalan Hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Jan. 10, 2013 In Use
10139-0321-01 10139-0321 Melphalan Hydrochloride Melphalan Hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Oct. 27, 2009 In Use
67457-0579-01 67457-0579 Melphalan Hydrochloride Melphalan Hydrochloride Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous Sept. 29, 2014 May 31, 2021 In Use
25021-0258-61 25021-0258 Melphalan Hydrochloride Melphalan Hydrochloride 50.0 mg/10ml Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous April 1, 2024 In Use
54868-4339-00 54868-4339 Melphalan Alkeran Chemotherapy Alkylating Agent Nitrogen Mustard Oral Aug. 15, 2005 June 30, 2012 No Longer Used
54868-4339-01 54868-4339 Melphalan Alkeran Chemotherapy Alkylating Agent Nitrogen Mustard Oral Aug. 15, 2005 June 30, 2012 No Longer Used
54868-4339-03 54868-4339 Melphalan Alkeran Chemotherapy Alkylating Agent Nitrogen Mustard Oral Aug. 15, 2005 June 30, 2012 No Longer Used
54868-4339-04 54868-4339 Melphalan Alkeran Chemotherapy Alkylating Agent Nitrogen Mustard Oral Aug. 15, 2005 June 30, 2012 No Longer Used
68152-0109-00 68152-0109 Melphalan Evomela 50.0 mg/10mL Chemotherapy Alkylating Agent Nitrogen Mustard Intravenous March 31, 2016 March 31, 2022 No Longer Used
52609-0001-05 52609-0001 Melphalan Alkeran 2.0 mg/1 Chemotherapy Alkylating Agent Nitrogen Mustard Oral Jan. 1, 2011 In Use
00015-0595-01 00015-0595 Megestrol Acetate Megace Hormonal Therapy Progestin Analog Jan. 1, 2005 May 31, 2005 No Longer Used
00015-0596-41 00015-0596 Megestrol Acetate Megace Hormonal Therapy Progestin Analog Jan. 1, 2005 Aug. 31, 2006 No Longer Used
00182-1863-89 00182-1863 Megestrol Acetate Megestrol Acetate Hormonal Therapy Progestin Analog Oral Jan. 1, 2009 Jan. 2, 2009 No Longer Used
00182-1864-00 00182-1864 Megestrol Acetate Megestrol Acetate Hormonal Therapy Progestin Analog Oral June 3, 2010 Nov. 30, 2010 No Longer Used

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