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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category (Descending) Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
66435-0410-05 66435-0410 Topotecan Hydrochloride Topotecan Hydrochloride 4.0 mg/4mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous Dec. 2, 2010 Oct. 31, 2014 No Longer Used
66758-0040-01 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 17, 2010 March 31, 2014 No Longer Used
66758-0040-02 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 1, 2009 March 31, 2014 No Longer Used
66758-0040-07 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 17, 2010 March 31, 2014 No Longer Used
66758-0040-08 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 1, 2009 Dec. 31, 2013 No Longer Used
66758-0041-01 66758-0041 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 1, 2009 Nov. 30, 2018 In Use
66758-0042-01 66758-0042 Epirubicin Hydrochloride Epirubicin Hydrochloride 2.0 mg/mL Chemotherapy Antitumor Antibiotic Anthracycline Intravenous Dec. 22, 2009 May 31, 2014 In Use
66758-0042-02 66758-0042 Epirubicin Hydrochloride Epirubicin Hydrochloride 2.0 mg/mL Chemotherapy Antitumor Antibiotic Anthracycline Intravenous Dec. 22, 2009 May 31, 2014 In Use
66758-0043-01 66758-0043 Paclitaxel Paclitaxel 6.0 mg/mL Chemotherapy Antimitotic Agent Taxane Intravenous Jan. 2, 2008 Feb. 7, 2016 In Use
66758-0043-02 66758-0043 Paclitaxel Paclitaxel 6.0 mg/mL Chemotherapy Antimitotic Agent Taxane Intravenous Jan. 2, 2008 Feb. 7, 2016 In Use
66758-0043-03 66758-0043 Paclitaxel Paclitaxel 6.0 mg/mL Chemotherapy Antimitotic Agent Taxane Intravenous Jan. 2, 2008 Feb. 7, 2016 In Use
66758-0044-01 66758-0044 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Sept. 10, 2008 Oct. 7, 2014 In Use
66758-0044-03 66758-0044 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Sept. 10, 2008 Oct. 7, 2014 In Use
66758-0047-01 66758-0047 Carboplatin Carboplatin 10.0 mg/mL Chemotherapy Alkylating Agent Platinum Compound Intravenous Jan. 31, 2010 March 15, 2015 In Use
66758-0047-02 66758-0047 Carboplatin Carboplatin 10.0 mg/mL Chemotherapy Alkylating Agent Platinum Compound Intravenous Jan. 31, 2010 July 15, 2015 In Use
66758-0047-03 66758-0047 Carboplatin Carboplatin 10.0 mg/mL Chemotherapy Alkylating Agent Platinum Compound Intravenous Jan. 31, 2010 July 19, 2015 In Use
66758-0047-04 66758-0047 Carboplatin Carboplatin 10.0 mg/mL Chemotherapy Alkylating Agent Platinum Compound Intravenous Jan. 31, 2010 May 2, 2015 In Use
66758-0048-01 66758-0048 Irinotecan Hydrochloride Irinotecan Hydrochloride 20.0 mg/mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous Nov. 30, 2009 May 27, 2018 In Use
66758-0048-02 66758-0048 Irinotecan Hydrochloride Irinotecan Hydrochloride 20.0 mg/mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous Nov. 30, 2009 May 27, 2018 In Use
66758-0051-01 66758-0051 Topotecan Topotecan 1.0 mg/mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous Feb. 25, 2011 In Use
66758-0051-03 66758-0051 Topotecan Topotecan 1.0 mg/mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous Feb. 25, 2011 In Use
66758-0051-05 66758-0051 Topotecan Topotecan 1.0 mg/mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous Feb. 25, 2011 In Use
66758-0054-01 66758-0054 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous May 2, 2011 May 2, 2011 In Use
66758-0054-02 66758-0054 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous May 2, 2011 May 2, 2011 In Use
66758-0055-01 66758-0055 Idarubicin Hydrochloride Idarubicin Hydrochloride 1.0 mg/mL Chemotherapy Antitumor Antibiotic Anthracycline Intravenous March 29, 2011 March 29, 2011 In Use
66758-0055-03 66758-0055 Idarubicin Hydrochloride Idarubicin Hydrochloride 1.0 mg/mL Chemotherapy Antitumor Antibiotic Anthracycline Intravenous March 29, 2011 March 29, 2011 In Use
66758-0055-05 66758-0055 Idarubicin Hydrochloride Idarubicin Hydrochloride 1.0 mg/mL Chemotherapy Antitumor Antibiotic Anthracycline Intravenous March 29, 2011 March 29, 2011 In Use
66828-0030-01 66828-0030 Imatinib Mesylate Gleevec 100.0 mg/1 Chemotherapy Tyrosine Kinase Inhibitor BCR-ABL Oral May 15, 2001 In Use
67253-0320-10 67253-0320 METHOTREXATE Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 7, 1953 Feb. 28, 2021 No Longer Used
67253-0320-36 67253-0320 METHOTREXATE Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 7, 1953 Feb. 28, 2021 No Longer Used
67457-0221-02 67457-0221 Methotrexate Methotrexate 1.0 g/40mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 27, 2012 Nov. 1, 2014 No Longer Used
67457-0221-10 67457-0221 Methotrexate Methotrexate 1.0 g/40mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 27, 2012 Nov. 1, 2014 No Longer Used
67457-0221-40 67457-0221 Methotrexate Methotrexate 1.0 g/40mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 27, 2012 Feb. 1, 2015 No Longer Used
67457-0434-51 67457-0434 Paclitaxel Paclitaxel 300.0 mg/50mL Chemotherapy Antimitotic Agent Taxane Intravenous Aug. 7, 2014 March 31, 2021 No Longer Used
67457-0449-17 67457-0449 Paclitaxel Paclitaxel 100.0 mg/16.7mL Chemotherapy Antimitotic Agent Taxane Intravenous Aug. 7, 2014 Oct. 31, 2020 No Longer Used
67457-0454-50 67457-0454 Cytarabine Cytarabine 20.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous, Subcutaneous Dec. 14, 2011 Dec. 31, 2021 No Longer Used
67457-0462-01 67457-0462 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 1.0 g/25mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Sept. 22, 2014 April 30, 2021 No Longer Used
67457-0463-02 67457-0463 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 2.0 g/50mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous July 24, 2014 June 30, 2021 No Longer Used
67457-0464-20 67457-0464 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 200.0 mg/5mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous July 24, 2014 June 30, 2021 No Longer Used
67457-0466-10 67457-0466 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous March 30, 2012 April 30, 2021 No Longer Used
67457-0467-21 67457-0467 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous March 30, 2012 March 31, 2016 No Longer Used
67457-0467-99 67457-0467 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous March 30, 2012 March 31, 2016 No Longer Used
67457-0468-50 67457-0468 Oxaliplatin Oxaliplatin 50.0 mg/10mL Chemotherapy Alkylating Agent Platinum Compound Intravenous Aug. 9, 2012 Dec. 31, 2017 No Longer Used
67457-0471-52 67457-0471 Paclitaxel Paclitaxel 30.0 mg/5mL Chemotherapy Antimitotic Agent Taxane Intravenous Aug. 7, 2014 Feb. 28, 2021 No Longer Used
67457-0474-04 67457-0474 Topotecan Hydrochloride Topotecan Hydrochloride 4.0 mg/mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous Aug. 29, 2012 Dec. 31, 2017 No Longer Used
67457-0476-10 67457-0476 Oxaliplatin Oxaliplatin 100.0 mg/20mL Chemotherapy Alkylating Agent Platinum Compound Intravenous Aug. 9, 2012 Dec. 31, 2017 No Longer Used
67457-0480-40 67457-0480 Methotrexate Methotrexate 25.0 mg/mL, 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Oct. 3, 2017 June 30, 2021 No Longer Used
67457-0485-08 67457-0485 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous March 30, 2012 Dec. 31, 2016 No Longer Used
67457-0485-99 67457-0485 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous March 30, 2012 Dec. 31, 2016 No Longer Used
67457-0486-04 67457-0486 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous March 30, 2012 April 30, 2016 No Longer Used
67457-0486-99 67457-0486 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous March 30, 2012 April 30, 2016 No Longer Used
67457-0615-20 67457-0615 Cytarabine Cytarabine 2.0 g/20mL Chemotherapy Antimetabolite Pyrimidine Analog Intrathecal, Intravenous, Subcutaneous Jan. 31, 2012 Feb. 1, 2012 No Longer Used
67877-0537-07 67877-0537 Temozolomide Temozolomide 5.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral April 28, 2017 In Use
67877-0537-14 67877-0537 Temozolomide Temozolomide 5.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral April 28, 2017 In Use
67877-0538-07 67877-0538 Temozolomide Temozolomide 20.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral April 28, 2017 In Use
67877-0538-14 67877-0538 Temozolomide Temozolomide 20.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral April 28, 2017 In Use
67877-0539-07 67877-0539 Temozolomide Temozolomide 100.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral April 28, 2017 In Use
67877-0539-14 67877-0539 Temozolomide Temozolomide 100.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral April 28, 2017 In Use
67877-0540-07 67877-0540 Temozolomide Temozolomide 140.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral April 28, 2017 In Use
67877-0540-14 67877-0540 Temozolomide Temozolomide 140.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral April 28, 2017 In Use
67877-0541-07 67877-0541 Temozolomide Temozolomide 180.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral April 28, 2017 In Use
67877-0541-14 67877-0541 Temozolomide Temozolomide 180.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral April 28, 2017 In Use
67877-0542-07 67877-0542 Temozolomide Temozolomide 250.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral April 28, 2017 In Use
68001-0282-22 68001-0282 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 38.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous July 25, 2011 Aug. 1, 2021 No Longer Used
68001-0282-25 68001-0282 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 38.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous May 23, 2016 Aug. 1, 2021 No Longer Used
68001-0282-26 68001-0282 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 38.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous May 23, 2016 Aug. 1, 2021 No Longer Used
68001-0282-27 68001-0282 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 38.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous May 23, 2016 Aug. 1, 2021 No Longer Used
68001-0284-25 68001-0284 Irinotecan Hydrochloride Irinotecan Hydrochloride 20.0 mg/mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous May 31, 2016 March 1, 2021 In Use
68001-0284-34 68001-0284 Irinotecan Hydrochloride Irinotecan Hydrochloride 20.0 mg/mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous May 31, 2016 March 1, 2021 In Use
68001-0425-35 68001-0425 Irinotecan Hydrochloride Irinotecan Hydrochloride 20.0 mg/mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous July 7, 2020 Aug. 11, 2021 No Longer Used
68001-0426-22 68001-0426 Irinotecan Hydrochloride Irinotecan Hydrochloride 20.0 mg/mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous July 7, 2020 Aug. 11, 2021 No Longer Used
68151-1305-00 68151-1305 Bromocriptine Mesylate Bromocriptine Mesylate 2.5 mg/1 Chemotherapy Dopamine Agonist Ergot Derivative Oral April 1, 2014 No Longer Used
68382-0775-01 68382-0775 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Feb. 9, 2017 In Use
68382-0775-05 68382-0775 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Feb. 9, 2017 In Use
68382-0775-10 68382-0775 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Feb. 9, 2017 In Use
68382-0775-16 68382-0775 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Feb. 9, 2017 In Use
68382-0775-60 68382-0775 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Feb. 9, 2017 In Use
68382-0775-77 68382-0775 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Feb. 9, 2017 In Use
69097-0313-37 69097-0313 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 200.0 mg/5mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous July 25, 2011 In Use
69097-0314-42 69097-0314 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 1.0 g/25mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous July 25, 2011 In Use
69097-0369-32 69097-0369 Docetaxel Anhydrous Docetaxel Anhydrous 20.0 mg/2mL Chemotherapy Antimitotic Agent Taxane Intravenous Aug. 24, 2018 Aug. 26, 2020 No Longer Used
69097-0371-37 69097-0371 Docetaxel Anhydrous Docetaxel Anhydrous 80.0 mg/8mL Chemotherapy Antimitotic Agent Taxane Intravenous Aug. 24, 2018 Aug. 26, 2020 In Use
69097-0805-40 69097-0805 Azacitidine Azacitidine For 100.0 mg/1 Chemotherapy Antimetabolite Pyrimidine Analog Intravenous, Subcutaneous March 26, 2019 In Use
69171-0398-01 69171-0398 Irinotecan Hydrochloride Onivyde 4.3 mg/mL Chemotherapy Topoisomerase I Inhibitor Camptothecin Analogs Intravenous Oct. 22, 2015 Sept. 30, 2019 No Longer Used
69189-0063-01 69189-0063 Erlotinib Hydrochloride Tarceva 100.0 mg/1 Chemotherapy Tyrosine Kinase Inhibitor EGFR Oral April 1, 2015 May 24, 2017 No Longer Used
69189-0382-01 69189-0382 Cyclophosphamide Cyclophosphamide 25.0 mg/1 Chemotherapy Alkylating Agent Nitrogen Mustard Oral Aug. 18, 2015 May 24, 2017 No Longer Used
69189-0383-01 69189-0383 Cyclophosphamide Cyclophosphamide 50.0 mg/1 Chemotherapy Alkylating Agent Nitrogen Mustard Oral April 23, 2015 May 24, 2017 No Longer Used
69189-0403-01 69189-0403 Imatinib Mesylate Gleevec 100.0 mg/1 Chemotherapy Tyrosine Kinase Inhibitor BCR-ABL Oral March 1, 2015 May 24, 2017 No Longer Used
69189-4581-01 69189-4581 Mercaptopurine Mercaptopurine 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral March 1, 2015 May 24, 2017 No Longer Used
69189-7096-01 69189-7096 Bromocriptine Mesylate Bromocriptine Mesylate 5.0 mg/1 Chemotherapy Dopamine Agonist Ergot Derivative Oral March 8, 2016 May 24, 2017 No Longer Used
69189-7638-01 69189-7638 Temozolomide Temozolomide 140.0 mg/1 Chemotherapy Alkylating Agent Tetrazine Oral June 11, 2015 May 24, 2017 No Longer Used
69639-0120-01 69639-0120 Mechlorethamine hydrochloride VALCHLOR 0.012 g/60g Chemotherapy Alkylating Agent Nitrogen Mustard TOPICAL Nov. 8, 2018 In Use
69945-0450-01 69945-0450 sodium iodide, i-131 Sodium Iodide I-131 5.0 mCi/mL Chemotherapy Radiopharmaceutical Iodine 131 Oral Oct. 27, 2015 July 1, 2018 No Longer Used
69945-0450-02 69945-0450 sodium iodide, i-131 Sodium Iodide I-131 5.0 mCi/mL Chemotherapy Radiopharmaceutical Iodine 131 Oral Oct. 27, 2015 July 1, 2018 No Longer Used
69945-0450-03 69945-0450 sodium iodide, i-131 Sodium Iodide I-131 5.0 mCi/mL Chemotherapy Radiopharmaceutical Iodine 131 Oral Oct. 27, 2015 July 1, 2018 No Longer Used
69945-0450-04 69945-0450 sodium iodide, i-131 Sodium Iodide I-131 5.0 mCi/mL Chemotherapy Radiopharmaceutical Iodine 131 Oral Oct. 27, 2015 July 1, 2018 No Longer Used
69945-0450-05 69945-0450 sodium iodide, i-131 Sodium Iodide I-131 5.0 mCi/mL Chemotherapy Radiopharmaceutical Iodine 131 Oral Oct. 27, 2015 July 1, 2018 No Longer Used
69945-0450-07 69945-0450 sodium iodide, i-131 Sodium Iodide I-131 5.0 mCi/mL Chemotherapy Radiopharmaceutical Iodine 131 Oral Oct. 27, 2015 July 1, 2018 No Longer Used
69945-0451-02 69945-0451 sodium iodide, i-131 Sodium Iodide I-131 25.0 mCi/mL Chemotherapy Radiopharmaceutical Iodine 131 Oral Oct. 27, 2015 July 1, 2018 No Longer Used
69945-0451-03 69945-0451 sodium iodide, i-131 Sodium Iodide I-131 25.0 mCi/mL Chemotherapy Radiopharmaceutical Iodine 131 Oral Oct. 27, 2015 July 1, 2018 No Longer Used

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