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NDC-11 (Package) NDC-9 (Product) Generic Name (Ascending) Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
66758-0040-01 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 17, 2010 March 31, 2014 No Longer Used
66758-0040-02 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 1, 2009 March 31, 2014 No Longer Used
66758-0040-07 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 17, 2010 March 31, 2014 No Longer Used
66758-0040-08 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 1, 2009 Dec. 31, 2013 No Longer Used
66758-0041-01 66758-0041 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 1, 2009 Nov. 30, 2018 In Use
70518-1251-00 70518-1251 Methotrexate Sodium Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral June 11, 2018 March 27, 2020 No Longer Used
70518-2711-00 70518-2711 Methotrexate Sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral April 27, 2020 In Use
54868-4716-00 54868-4716 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intravenous, subcutaneous, intramuscular Dec. 16, 2002 Dec. 31, 2010 No Longer Used
55390-0031-10 55390-0031 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous May 1, 1996 Oct. 31, 2012 No Longer Used
55390-0032-10 55390-0032 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous May 1, 1996 Oct. 31, 2012 No Longer Used
61703-0351-59 61703-0351 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Jan. 29, 2010 Feb. 1, 2010 No Longer Used
61703-0352-07 61703-0352 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Jan. 29, 2010 Feb. 1, 2010 No Longer Used
10139-0062-02 10139-0062 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intravenous, subcutaneous, intramuscular May 6, 2013 Jan. 31, 2014 No Longer Used
10139-0062-10 10139-0062 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intravenous, subcutaneous, intramuscular May 6, 2013 Jan. 31, 2014 No Longer Used
10139-0062-40 10139-0062 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intravenous, subcutaneous, intramuscular May 6, 2013 Jan. 31, 2014 No Longer Used
55390-0033-10 55390-0033 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog May 1, 1996 Oct. 31, 2012 No Longer Used
55390-0034-10 55390-0034 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog May 1, 1996 Oct. 31, 2012 No Longer Used
55390-0143-01 55390-0143 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Sept. 6, 2005 May 31, 2013 No Longer Used
49349-0314-02 49349-0314 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Feb. 2, 2010 Nov. 14, 2011 No Longer Used
49349-0406-02 49349-0406 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral May 27, 2010 Jan. 13, 2012 No Longer Used
54868-3826-00 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 5, 2007 In Use
54868-3826-01 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 5, 2007 In Use
54868-3826-02 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 5, 2007 In Use
54868-3826-03 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 5, 2007 In Use
54868-3826-04 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 5, 2007 In Use
54868-3826-05 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 5, 2007 In Use
54868-3826-06 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 5, 2007 In Use
54868-3826-07 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 5, 2007 In Use
54868-3826-08 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 5, 2007 In Use
54868-3826-09 54868-3826 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 5, 2007 In Use
61786-0417-02 61786-0417 Methotrexate sodium Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Sept. 23, 2015 Jan. 24, 2017 No Longer Used
61786-0417-03 61786-0417 Methotrexate sodium Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral March 14, 2016 Jan. 24, 2017 No Longer Used
61786-0417-07 61786-0417 Methotrexate sodium Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Nov. 3, 2015 Jan. 24, 2017 No Longer Used
21695-0111-00 21695-0111 Methotrexate sodium Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Oct. 15, 1990 In Use
21695-0111-30 21695-0111 Methotrexate sodium Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Oct. 15, 1990 In Use
75840-0111-00 75840-0111 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Oct. 1, 2012 In Use
75840-0111-01 75840-0111 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Oct. 1, 2012 In Use
63629-1472-01 63629-1472 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral June 4, 2014 In Use
63629-1472-02 63629-1472 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Jan. 16, 2008 In Use
63629-1472-03 63629-1472 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral April 19, 2010 In Use
63629-1472-04 63629-1472 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral July 19, 2010 In Use
63629-1472-05 63629-1472 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 11, 2012 In Use
63629-1472-06 63629-1472 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 26, 2019 In Use
63629-1472-07 63629-1472 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Sept. 20, 2021 In Use
63629-1472-08 63629-1472 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Sept. 20, 2021 In Use
00054-4550-15 00054-4550 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 1, 1994 May 31, 2025 In Use
00054-4550-25 00054-4550 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 1, 1994 In Use
00054-8550-25 00054-8550 Methotrexate sodium Methotrexate Sodium 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Aug. 1, 1994 Aug. 31, 2024 In Use
50090-2345-04 50090-2345 Methotrexate, Methotrexate sodium Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral April 25, 2016 July 31, 2018 In Use
50090-2345-09 50090-2345 Methotrexate, Methotrexate sodium Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral April 8, 2016 In Use

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