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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
57377-0025-01 57377-0025 Estradiol pellet Estra-25 25.0 mg/1 Hormonal Therapy Estrogen Subcutaneous Jan 1, 2017 In Use
00430-0721-24 00430-0721 Estradiol ESTRACE 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 26, 2011 Aug 31, 2025 No Longer Used
70700-0275-22 70700-0275 ESTRADIOL VALERATE Estradiol valerate 40.0 mg/mL Hormonal Therapy Estrogen Intramuscular May 1, 2023 In Use
21695-0623-00 21695-0623 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 In Use
63629-4788-01 63629-4788 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec 22, 2021 In Use
72789-0489-30 72789-0489 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Feb 20, 2025 In Use
42806-0088-05 42806-0088 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Apr 10, 2017 In Use
55154-0219-08 55154-0219 Estrogens, Conjugated Premarin 0.9 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 In Use
00046-1104-51 00046-1104 Estrogens, Conjugated Premarin 1.25 mg/1 Hormonal Therapy Estrogen Oral Sep 1, 2004 Apr 30, 2013 In Use
51655-0227-26 51655-0227 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Feb 15, 2023 In Use
68788-7102-03 68788-7102 ESTRADIOL ESTRADIOL 1.0 mg/1 Hormonal Therapy Estrogen Oral Mar 12, 2018 In Use
63629-4788-03 63629-4788 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec 22, 2021 In Use
50742-0388-10 50742-0388 Estrogens, conjugated Estrogens, conjugated 0.45 mg/1 Hormonal Therapy Estrogen Oral Oct 16, 2025 In Use
63629-3755-04 63629-3755 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov 24, 2008 Mar 30, 2018 No Longer Used
00555-0899-02 00555-0899 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Oct 28, 1997 In Use
00378-1452-01 00378-1452 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jun 17, 1999 May 31, 2021 No Longer Used
71335-2387-06 71335-2387 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 8, 2024 In Use
68788-9416-06 68788-9416 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 4, 2014 Sep 9, 2019 No Longer Used
00046-1102-91 00046-1102 Estrogens, Conjugated Premarin 0.625 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 In Use
61919-0278-60 61919-0278 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug 12, 2019 In Use
42806-0089-05 42806-0089 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Apr 10, 2017 In Use
55289-0603-07 55289-0603 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Dec 23, 2009 Nov 23, 2021 No Longer Used
70518-3818-00 70518-3818 ESTRADIOL ESTRADIOL 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug 3, 2023 In Use
16590-0052-71 16590-0052 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Oct 22, 1997 In Use
61919-0198-30 61919-0198 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Nov 25, 2015 In Use

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