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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
50242-0717-01 50242-0717 Cobimetinib Cotellic 20.0 mg/1 Chemotherapy MAPK/MEK Inhibitor BRAF Oral Nov 10, 2015 In Use
71779-0623-01 71779-0623 Avutometinib potassium and defactinib hydrochloride AVMAPKI FAKZYNJA CO-PACK 0.8 mg/1, 200.0 mg/1 Chemotherapy MEK Inhibitor, Tyrosine Kinase Inhibitor MEK1/2, ERK1/2, KRAS, FAK Oral May 8, 2025 In Use
00078-1161-47 00078-1161 Trametinib Mekinist 0.05 mg/mL Chemotherapy MEK Inhibitor BRAF Oral Mar 16, 2023 In Use
00310-0610-28 00310-0610 SELUMETINIB KOSELUGO 10.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Jun 11, 2021 In Use
00310-0625-28 00310-0625 SELUMETINIB KOSELUGO 25.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Jun 11, 2021 In Use
70255-0010-02 70255-0010 BINIMETINIB MEKTOVI 15.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Jun 27, 2018 In Use
00173-0849-13 00173-0849 Trametinib Mekinist 0.5 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Jun 17, 2013 Dec 31, 2016 No Longer Used
00310-0640-60 00310-0640 SELUMETINIB KOSELUGO 7.5 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Sep 10, 2025 In Use
00173-0858-13 00173-0858 Trametinib Mekinist 1.0 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Jun 17, 2013 Oct 5, 2015 No Longer Used
00173-0848-13 00173-0848 Trametinib Mekinist 2.0 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Jun 17, 2013 Dec 31, 2016 No Longer Used
00078-0668-15 00078-0668 Trametinib Mekinist 2.0 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Mar 17, 2016 Apr 30, 2024 No Longer Used
00310-0625-60 00310-0625 SELUMETINIB KOSELUGO 25.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Apr 16, 2020 In Use
70255-0010-03 70255-0010 BINIMETINIB MEKTOVI 15.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Jun 27, 2018 In Use
00078-0666-15 00078-0666 Trametinib Mekinist 0.5 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Mar 17, 2016 Oct 31, 2023 No Longer Used
00310-0635-60 00310-0635 SELUMETINIB KOSELUGO 5.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Sep 10, 2025 In Use
00310-0610-60 00310-0610 SELUMETINIB KOSELUGO 10.0 mg/1 Chemotherapy MEK Inhibitor MEK 1/2 Oral Apr 16, 2020 In Use
00173-0848-65 00173-0848 Trametinib Mekinist 2.0 mg/1 Chemotherapy MEK Inhibitor BRAF Oral Jun 17, 2013 Nov 30, 2016 No Longer Used
00024-5151-75 00024-5151 Rasburicase Elitek Ancillary Therapy Metabolic Agent Enzyme Jun 1, 2006 In Use
00024-5150-10 00024-5150 Rasburicase Elitek Ancillary Therapy Metabolic Agent Enzyme Jul 12, 2002 In Use
70860-0217-10 70860-0217 Arsenic Trioxide Arsenic Trioxide 1.0 mg/mL Chemotherapy Miscellaneous Agent PML/RARa Intravenous Nov 30, 2020 Oct 31, 2024 In Use
71335-2120-01 71335-2120 Pilocarpine hydrchloride Pilocarpine hydrchloride 5.0 mg/1 Ancillary Therapy Miscellaneous Agent Cholinergic Agonist Oral Jun 20, 2022 In Use
68084-0284-01 68084-0284 Hydroxyurea Hydroxyurea 500.0 mg/1 Chemotherapy Miscellaneous Agent Antimetabolite/Organooxygen Oral Sep 17, 2008 In Use
49884-0724-01 49884-0724 Hydroxyurea Hydroxyurea 500.0 mg/1 Chemotherapy Miscellaneous Agent Antimetabolite/Organooxygen Oral Feb 24, 1999 In Use
42291-0321-01 42291-0321 Hydroxyurea Hydroxyurea 500.0 mg/1 Chemotherapy Miscellaneous Agent Antimetabolite/Organooxygen Oral Jul 23, 2013 In Use
63459-0601-06 63459-0601 Arsenic Trioxide Trisenox 2.0 mg/mL Chemotherapy Miscellaneous Agent PML/RARa Intravenous Dec 22, 2017 In Use

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