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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
16590-0052-71 16590-0052 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Oct 22, 1997 In Use
66993-0296-02 66993-0296 Estrogens, conjugated Conjugated Estrogens 0.45 mg/1 Hormonal Therapy Estrogen Oral Feb 27, 2026 In Use
00378-1454-05 00378-1454 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jun 17, 1999 Jul 31, 2021 No Longer Used
00430-0720-24 00430-0720 Estradiol ESTRACE 0.5 mg/1 Hormonal Therapy Estrogen Oral Dec 26, 2011 Aug 31, 2025 No Longer Used
21695-0623-00 21695-0623 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 In Use
43063-0717-90 43063-0717 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Oct 12, 2016 Oct 31, 2023 No Longer Used
49999-0109-00 49999-0109 conjugated estrogens Premarin 0.625 mg/1 Hormonal Therapy Estrogen Oral Mar 21, 2012 Jan 1, 2013 In Use
55700-0458-30 55700-0458 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov 18, 2016 In Use
68788-8626-06 68788-8626 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Apr 9, 2024 In Use
70934-0927-30 70934-0927 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov 24, 2021 In Use
00179-0074-70 00179-0074 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Oct 20, 2010 In Use
50090-1704-00 50090-1704 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb 18, 2015 In Use
21695-0623-30 21695-0623 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 In Use
55154-0217-04 55154-0217 conjugated estrogens Premarin 0.3 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 May 31, 2013 No Longer Used
68788-7961-01 68788-7961 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 16, 2021 In Use
00555-0886-02 00555-0886 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Oct 28, 1997 In Use
50090-7480-00 50090-7480 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 20, 2024 In Use
68788-7332-06 68788-7332 ESTRADIOL ESTRADIOL 0.5 mg/1 Hormonal Therapy Estrogen Oral Mar 12, 2019 In Use
68788-9416-01 68788-9416 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 4, 2014 Sep 9, 2019 No Longer Used
68788-9416-06 68788-9416 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec 4, 2014 Sep 9, 2019 No Longer Used
43063-0201-30 43063-0201 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec 10, 2009 Oct 2, 2017 No Longer Used
54868-4031-01 54868-4031 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral May 7, 2003 In Use
54868-0365-01 54868-0365 Estrogens, Conjugated Premarin Hormonal Therapy Estrogen Oral Jul 26, 1995 Jul 6, 2010 No Longer Used
64205-0488-30 64205-0488 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 In Use
00574-0870-05 00574-0870 Estradiol Valerate Estradiol Valerate 20.0 mg/mL Hormonal Therapy Estrogen Intramuscular Mar 31, 2010 In Use

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