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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
51862-0333-05 51862-0333 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug 3, 2016 Oct 31, 2023 No Longer Used
00781-3030-75 00781-3030 Estradiol Valerate Estradiol Valerate Hormonal Therapy Estrogen Oct 4, 2007 Jan 31, 2010 No Longer Used
54868-4370-01 54868-4370 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jun 9, 2003 In Use
67046-1568-03 67046-1568 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jun 17, 2025 In Use
70518-3922-01 70518-3922 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jan 13, 2025 In Use
51655-0227-52 51655-0227 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Jun 28, 2023 In Use
51862-0333-01 51862-0333 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Aug 3, 2016 May 31, 2023 No Longer Used
49999-0109-30 49999-0109 conjugated estrogens Premarin 0.625 mg/1 Hormonal Therapy Estrogen Oral Mar 21, 2012 Jan 1, 2013 In Use
00555-0886-01 00555-0886 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Oct 28, 1997 Jan 26, 2011 In Use
68071-3394-02 68071-3394 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 12, 2017 In Use
68788-8484-03 68788-8484 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jul 13, 2023 In Use
43353-0688-60 43353-0688 conjugated estrogens Premarin 0.625 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 In Use
49999-0083-30 49999-0083 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Mar 12, 2012 Nov 18, 2016 No Longer Used
33261-0667-60 33261-0667 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Oct 28, 1997 In Use
66993-0299-02 66993-0299 Estrogens, conjugated Conjugated Estrogens 1.25 mg/1 Hormonal Therapy Estrogen Oral Feb 27, 2026 In Use
00143-9291-01 00143-9291 Estradiol Valerate Estradiol Valerate 40.0 mg/mL Hormonal Therapy Estrogen Intramuscular Apr 21, 2020 In Use
00179-1999-88 00179-1999 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Oct 14, 2015 May 31, 2020 No Longer Used
35356-0250-00 35356-0250 Estrogens, Conjugated, conjugated estrogens Premarin 0.9 mg/1 Hormonal Therapy Estrogen Oral Mar 22, 2012 Dec 31, 2014 No Longer Used
61570-0074-01 61570-0074 Esterified Estrogens Menest 1.25 mg/1 Hormonal Therapy Estrogen Oral Sep 28, 1977 Apr 30, 2026 In Use
54868-0365-00 54868-0365 Estrogens, Conjugated Premarin Hormonal Therapy Estrogen Oral Jul 26, 1995 Jun 30, 2012 No Longer Used
71335-2477-02 71335-2477 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Sep 3, 2024 In Use
00179-1999-01 00179-1999 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jul 1, 2008 No Longer Used
42023-0111-01 42023-0111 Estradiol Valerate Delestrogen 20.0 mg/mL Hormonal Therapy Estrogen Intramuscular Nov 1, 2007 In Use
42023-0134-01 42023-0134 Estradiol Valerate Estradiol Valerate 10.0 mg/mL Hormonal Therapy Estrogen Intramuscular Jun 1, 2012 Feb 28, 2016 No Longer Used
42806-0089-05 42806-0089 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Apr 10, 2017 In Use

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