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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
57377-0025-01 57377-0025 Estradiol pellet Estra-25 25.0 mg/1 Hormonal Therapy Estrogen Subcutaneous Jan 1, 2017 In Use
50090-1941-02 50090-1941 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb 9, 2017 Feb 9, 2017 No Longer Used
66267-0092-30 66267-0092 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Sep 30, 2016 Dec 31, 2017 In Use
60429-0327-01 60429-0327 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Nov 26, 2014 Mar 31, 2017 No Longer Used
16590-0052-71 16590-0052 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Oct 22, 1997 In Use
66267-0093-91 66267-0093 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Oct 28, 1997 Dec 13, 2018 No Longer Used
43063-0446-90 43063-0446 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Apr 18, 2013 Jan 24, 2019 In Use
00555-0887-14 00555-0887 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Oct 28, 1997 Jan 26, 2011 In Use
00430-0720-24 00430-0720 Estradiol ESTRACE 0.5 mg/1 Hormonal Therapy Estrogen Oral Dec 26, 2011 Aug 31, 2025 In Use
68788-8484-09 68788-8484 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jul 13, 2023 In Use
70954-0566-10 70954-0566 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Sep 6, 2023 In Use
64205-0488-90 64205-0488 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Mar 14, 1996 In Use
70934-0927-90 70934-0927 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov 24, 2021 In Use
70518-3910-00 70518-3910 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Nov 7, 2023 In Use
55154-0217-00 55154-0217 conjugated estrogens Premarin 0.3 mg/1 Hormonal Therapy Estrogen Oral Jan 1, 2006 Feb 28, 2014 No Longer Used
50090-1343-00 50090-1343 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Nov 28, 2014 In Use
68788-9901-06 68788-9901 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Feb 13, 2012 Sep 9, 2019 No Longer Used
54868-4370-00 54868-4370 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jun 9, 2003 In Use
68071-3394-03 68071-3394 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 12, 2017 In Use
68788-7892-03 68788-7892 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Apr 23, 2021 May 30, 2023 No Longer Used
68071-3394-09 68071-3394 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 12, 2017 In Use
43063-0717-90 43063-0717 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Oct 12, 2016 Oct 31, 2023 No Longer Used
63629-3755-04 63629-3755 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov 24, 2008 Mar 30, 2018 No Longer Used
49999-0109-90 49999-0109 conjugated estrogens Premarin 0.625 mg/1 Hormonal Therapy Estrogen Oral Mar 21, 2012 Jun 1, 2012 In Use
69189-0886-01 69189-0886 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Jul 14, 2015 May 24, 2017 No Longer Used

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