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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class (Descending) Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
66336-0338-21 66336-0338 METHOTREXATE Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 7, 1953 In Use
66336-0338-30 66336-0338 METHOTREXATE Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 7, 1953 In Use
66758-0040-01 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 17, 2010 March 31, 2014 No Longer Used
66758-0040-02 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 1, 2009 March 31, 2014 No Longer Used
66758-0040-07 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 17, 2010 March 31, 2014 No Longer Used
66758-0040-08 66758-0040 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 1, 2009 Dec. 31, 2013 No Longer Used
66758-0041-01 66758-0041 Methotrexate Sodium Methotrexate Sodium 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 1, 2009 Nov. 30, 2018 In Use
66758-0044-01 66758-0044 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Sept. 10, 2008 Oct. 7, 2014 In Use
66758-0044-03 66758-0044 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Sept. 10, 2008 Oct. 7, 2014 In Use
66758-0054-01 66758-0054 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous May 2, 2011 May 2, 2011 In Use
66758-0054-02 66758-0054 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous May 2, 2011 May 2, 2011 In Use
67253-0320-10 67253-0320 METHOTREXATE Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 7, 1953 Feb. 28, 2021 No Longer Used
67253-0320-36 67253-0320 METHOTREXATE Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Dec. 7, 1953 Feb. 28, 2021 No Longer Used
67457-0221-02 67457-0221 Methotrexate Methotrexate 1.0 g/40mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 27, 2012 Nov. 1, 2014 No Longer Used
67457-0221-10 67457-0221 Methotrexate Methotrexate 1.0 g/40mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 27, 2012 Nov. 1, 2014 No Longer Used
67457-0221-40 67457-0221 Methotrexate Methotrexate 1.0 g/40mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous June 27, 2012 Feb. 1, 2015 No Longer Used
67457-0454-50 67457-0454 Cytarabine Cytarabine 20.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous, Subcutaneous Dec. 14, 2011 Dec. 31, 2021 No Longer Used
67457-0462-01 67457-0462 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 1.0 g/25mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Sept. 22, 2014 April 30, 2021 No Longer Used
67457-0463-02 67457-0463 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 2.0 g/50mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous July 24, 2014 June 30, 2021 No Longer Used
67457-0464-20 67457-0464 Gemcitabine Hydrochloride Gemcitabine Hydrochloride 200.0 mg/5mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous July 24, 2014 June 30, 2021 No Longer Used
67457-0466-10 67457-0466 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous March 30, 2012 April 30, 2021 No Longer Used
67457-0467-21 67457-0467 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous March 30, 2012 March 31, 2016 No Longer Used
67457-0467-99 67457-0467 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous March 30, 2012 March 31, 2016 No Longer Used
67457-0480-40 67457-0480 Methotrexate Methotrexate 25.0 mg/mL, 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Oct. 3, 2017 June 30, 2021 No Longer Used
67457-0485-08 67457-0485 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous March 30, 2012 Dec. 31, 2016 No Longer Used

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