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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class (Descending) Minor Class Administration Route Package Effective Date Package Discontinuation Date Status
70771-1058-09 70771-1058 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral Feb. 9, 2017 In Use
00781-3253-94 00781-3253 Azacitidine Azacitidine 100.0 mg/1 Chemotherapy Antimetabolite Pyrimidine Analog Intravenous, Subcutaneous Sept. 16, 2013 Feb. 28, 2025 In Use
16729-0131-30 16729-0131 FLUDARABINE FLUDARABINE PHOSPHATE 25.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous Nov. 22, 2022 In Use
55150-0393-01 55150-0393 AZACITIDINE AZACITIDINE 100.0 mg/4mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous, Subcutaneous Jan. 3, 2023 In Use
61703-0124-40 61703-0124 Methotrexate Methotrexate 25.0 mg/mL Chemotherapy Antimetabolite Folic Acid Analog Intramuscular, Intrathecal, Intravenous, Subcutaneous Jan. 9, 2023 In Use
71288-0145-10 71288-0145 Pemetrexed disodium Pemetrexed 100.0 mg/4.2mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Dec. 13, 2022 In Use
71288-0146-50 71288-0146 Pemetrexed disodium Pemetrexed 500.0 mg/20mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Dec. 13, 2022 In Use
71288-0147-50 71288-0147 Pemetrexed disodium Pemetrexed 750.0 mg/30mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Dec. 13, 2022 In Use
71288-0148-51 71288-0148 Pemetrexed disodium Pemetrexed 1.0 g/40mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Dec. 13, 2022 In Use
59923-0604-02 59923-0604 Fludarabine Phosphate Fludarabine Phosphate 25.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous Dec. 31, 2019 In Use
60763-0601-13 60763-0601 Mercaptopurine PURINETHOL 50.0 mg/1 Chemotherapy Antimetabolite Purine Analog Oral Jan. 15, 2022 In Use
67457-0450-10 67457-0450 Cladribine Cladribine 1.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous June 18, 2014 Dec. 31, 2022 No Longer Used
67457-0452-20 67457-0452 Cytarabine Cytarabine 2.0 g/20mL Chemotherapy Antimetabolite Pyrimidine Analog Intrathecal, Intravenous, Subcutaneous Jan. 31, 2012 Dec. 31, 2022 No Longer Used
69097-0905-67 69097-0905 Decitabine Decitabine 50.0 mg/10mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Sept. 17, 2021 In Use
70710-1726-01 70710-1726 Nelarabine Nelarabine 5.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous Nov. 17, 2021 In Use
70710-1726-08 70710-1726 Nelarabine Nelarabine 5.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous Nov. 17, 2021 In Use
00703-5775-01 00703-5775 Gemcitabine Gemcitabine Chemotherapy Antimetabolite Pyrimidine Analog Intravenous July 14, 2011 Jan. 31, 2014 No Longer Used
00703-5778-01 00703-5778 Gemcitabine Gemcitabine Chemotherapy Antimetabolite Pyrimidine Analog Intravenous July 14, 2011 Jan. 31, 2014 No Longer Used
00781-3282-75 00781-3282 Gemcitabine Hydrochloride Gemcitabine Hydrochloride Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Aug. 27, 2010 June 30, 2014 No Longer Used
00781-3283-79 00781-3283 Gemcitabine Hydrochloride Gemcitabine Hydrochloride Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Aug. 27, 2010 June 21, 2014 No Longer Used
50419-0511-06 50419-0511 Fludarabine Fludara Chemotherapy Antimetabolite Purine Analog Intravenous April 18, 1991 June 30, 2013 No Longer Used
52152-0609-55 52152-0609 Fludarabine phosphate Fludarabine phosphate Chemotherapy Antimetabolite Purine Analog Intravenous March 20, 2009 March 20, 2009 No Longer Used
54868-4716-00 54868-4716 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intravenous, subcutaneous, intramuscular Dec. 16, 2002 Dec. 31, 2010 No Longer Used
55390-0031-10 55390-0031 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous May 1, 1996 Oct. 31, 2012 No Longer Used
55390-0032-10 55390-0032 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous May 1, 1996 Oct. 31, 2012 No Longer Used
55390-0806-10 55390-0806 Cytarabine Cytarabine Chemotherapy Antimetabolite Pyrimidine Analog Intravenous, subcutaneous, intrathecal June 28, 1996 July 31, 2013 No Longer Used
55390-0807-10 55390-0807 Cytarabine Cytarabine Chemotherapy Antimetabolite Pyrimidine Analog Intravenous, subcutaneous, intrathecal June 28, 1996 March 31, 2013 No Longer Used
55390-0809-01 55390-0809 Cytarabine Cytarabine Chemotherapy Antimetabolite Pyrimidine Analog Intravenous, subcutaneous, intrathecal June 28, 1996 Dec. 31, 2010 No Longer Used
58468-0170-01 58468-0170 Fludarabine Fludara Chemotherapy Antimetabolite Purine Analog Intravenous July 29, 2010 March 9, 2012 No Longer Used
61703-0351-59 61703-0351 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Jan. 29, 2010 Feb. 1, 2010 No Longer Used
61703-0352-07 61703-0352 Methotrexate Sodium Methotrexate Chemotherapy Antimetabolite Folic Acid Analog Intra-arterial, Intramuscular, Intrathecal, Intravenous Jan. 29, 2010 Feb. 1, 2010 No Longer Used
16714-0928-01 16714-0928 Decitabine Decitabine 50.0 mg/10mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Feb. 18, 2019 In Use
42658-0010-01 42658-0010 Cladribine Cladribine 1.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous May 18, 2020 In Use
42658-0010-02 42658-0010 Cladribine Cladribine 1.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous April 1, 2020 In Use
42658-0010-91 42658-0010 Cladribine Cladribine 1.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous Feb. 28, 2023 In Use
00409-0004-04 00409-0004 PEMETREXED PEMETREXED 1.0 g/40mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Feb. 1, 2023 In Use
00409-0020-02 00409-0020 PEMETREXED PEMETREXED 100.0 mg/4mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Feb. 1, 2023 In Use
00409-0021-03 00409-0021 PEMETREXED PEMETREXED 500.0 mg/20mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous Feb. 1, 2023 In Use
00527-1242-02 00527-1242 Fludarabine Phosphate Fludarabine Phosphate 25.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous Dec. 31, 2019 In Use
43598-0142-06 43598-0142 Nelarabine Nelarabine 5.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous Jan. 9, 2023 In Use
43598-0142-11 43598-0142 Nelarabine Nelarabine 5.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous March 1, 2023 In Use
46708-0751-50 46708-0751 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous March 3, 2023 In Use
62332-0751-50 62332-0751 Fluorouracil Fluorouracil 50.0 mg/mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous March 3, 2023 In Use
63323-0102-13 63323-0102 GEMCITABINE GEMCITABINE 200.0 mg/5mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous July 26, 2011 In Use
63323-0102-94 63323-0102 GEMCITABINE GEMCITABINE 200.0 mg/5mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous July 26, 2011 In Use
63323-0102-10 63323-0102 GEMCITABINE GEMCITABINE 200.0 mg/5mL Chemotherapy Antimetabolite Pyrimidine Analog Intravenous Sept. 12, 2011 Jan. 31, 2014 In Use
68071-2961-04 68071-2961 Fluorouracil Fluorouracil 50.0 mg/g Chemotherapy Antimetabolite Pyrimidine Analog Topical March 20, 2023 In Use
70121-1232-01 70121-1232 Pemetrexed Pemetrexed disodium 100.0 mg/10mL Chemotherapy Antimetabolite Folic Acid Analog Intravenous May 16, 2023 In Use
70121-1743-04 70121-1743 Nelarabine Nelarabine 5.0 mg/mL Chemotherapy Antimetabolite Purine Analog Intravenous April 10, 2023 In Use
70518-3672-00 70518-3672 Methotrexate Methotrexate 2.5 mg/1 Chemotherapy Antimetabolite Folic Acid Analog Oral March 6, 2023 In Use

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