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NDC-11 (Package) NDC-9 (Product) Generic Name Brand Name Strength SEER*Rx Category Major Class Minor Class (Descending) Administration Route Package Effective Date Package Discontinuation Date Status
00378-1454-01 00378-1454 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral June 17, 1999 July 31, 2021 No Longer Used
00378-1454-05 00378-1454 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral June 17, 1999 July 31, 2021 No Longer Used
00378-1458-01 00378-1458 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral June 17, 1999 July 31, 2021 No Longer Used
00378-1458-05 00378-1458 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral June 17, 1999 Sept. 30, 2021 No Longer Used
00378-1458-77 00378-1458 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral June 17, 1999 July 31, 2021 No Longer Used
00591-0487-01 00591-0487 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral March 14, 1996 Dec. 31, 2017 In Use
00591-0487-05 00591-0487 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral March 14, 1996 June 30, 2018 In Use
00591-0488-01 00591-0488 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral March 14, 1996 June 30, 2018 In Use
00591-0488-05 00591-0488 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral March 14, 1996 Dec. 31, 2017 In Use
00591-0528-01 00591-0528 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral March 14, 1996 Dec. 31, 2017 In Use
00591-0528-05 00591-0528 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral March 14, 1996 Dec. 31, 2017 In Use
10544-0069-30 10544-0069 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral March 9, 2015 In Use
10544-0070-30 10544-0070 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral March 5, 2012 In Use
21695-0613-00 21695-0613 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral March 14, 1996 In Use
21695-0613-30 21695-0613 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral March 14, 1996 In Use
21695-0623-00 21695-0623 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral March 14, 1996 In Use
21695-0623-30 21695-0623 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral March 14, 1996 In Use
23155-0013-01 23155-0013 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Nov. 5, 2010 Sept. 23, 2019 In Use
23155-0014-01 23155-0014 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov. 5, 2010 Sept. 23, 2019 In Use
23155-0014-05 23155-0014 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Nov. 5, 2010 Sept. 23, 2019 In Use
23155-0015-01 23155-0015 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Nov. 5, 2010 Sept. 23, 2019 In Use
33261-0714-60 33261-0714 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Oct. 28, 1997 In Use
42806-0087-01 42806-0087 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral April 10, 2017 In Use
42806-0087-05 42806-0087 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral April 10, 2017 In Use
42806-0088-01 42806-0088 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral April 10, 2017 In Use
42806-0088-05 42806-0088 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral April 10, 2017 In Use
42806-0089-01 42806-0089 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral April 10, 2017 In Use
42806-0089-05 42806-0089 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral April 10, 2017 In Use
42806-0089-09 42806-0089 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral April 10, 2017 In Use
43063-0446-01 43063-0446 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral April 18, 2013 Jan. 24, 2019 In Use
43063-0446-30 43063-0446 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral April 18, 2013 Jan. 24, 2019 In Use
43063-0446-90 43063-0446 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral April 18, 2013 Jan. 24, 2019 In Use
43063-0651-30 43063-0651 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Jan. 22, 2016 Aug. 29, 2018 No Longer Used
49999-0083-30 49999-0083 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral March 12, 2012 Nov. 18, 2016 No Longer Used
50090-1343-00 50090-1343 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Nov. 28, 2014 In Use
50090-2624-00 50090-2624 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Nov. 16, 2016 In Use
50268-0290-11 50268-0290 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Sept. 30, 2014 March 19, 2018 No Longer Used
50268-0290-15 50268-0290 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Dec. 12, 2014 March 19, 2018 No Longer Used
50268-0291-11 50268-0291 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Sept. 30, 2014 March 19, 2018 No Longer Used
50268-0291-15 50268-0291 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 12, 2014 March 19, 2018 No Longer Used
50268-0292-11 50268-0292 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Sept. 30, 2014 March 19, 2018 No Longer Used
50268-0292-15 50268-0292 Estradiol Estradiol 2.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 12, 2014 March 19, 2018 No Longer Used
54868-4370-00 54868-4370 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral June 9, 2003 In Use
54868-4370-01 54868-4370 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral June 9, 2003 In Use
54868-4370-02 54868-4370 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral June 9, 2003 In Use
55154-6242-00 55154-6242 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 17, 2009 Sept. 30, 2013 No Longer Used
55154-6242-04 55154-6242 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 17, 2009 Sept. 30, 2012 No Longer Used
55154-6242-06 55154-6242 Estradiol Estradiol 1.0 mg/1 Hormonal Therapy Estrogen Oral Dec. 17, 2009 Sept. 30, 2013 No Longer Used
55289-0603-07 55289-0603 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Dec. 23, 2009 Nov. 23, 2021 No Longer Used
55289-0603-21 55289-0603 Estradiol Estradiol 0.5 mg/1 Hormonal Therapy Estrogen Oral Dec. 23, 2009 Nov. 23, 2021 No Longer Used

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