SEER Inquiry System - Report
Produced: 01/28/2023 1:39 AM
#1: AJCC Cancer Staging Manual, 400. 6th ed
#2: 2004 SEER Manual, C-702
This answer was provided in the context of CSv1 coding guidelines. The response may not be used after your registry database has been converted to CSv2.
Do not code spleen involvement when the only evidence is an enlarged spleen.
When imaging is the only diagnostic tool (no biopsy or splenectomy), spleen involvement is based on the presence of nodules and not on enlargement. Splenic enlargement alone (by physical exam or imaging) is insufficient to support involvement of spleen.