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This neoplasm is not reportable.
Name
Monoclonal B-cell lymphocytosis, non-chronic lymphocytic leukemia (CLL)-type
ICD-O-3 Morphology
9591/1: Monoclonal B-cell lymphocytosis, non-CLL-type
Effective
2021 and later
Reportability
This neoplasm is not reportable
Primary Site(s)
No primary site specified
This hematopoietic disease is not reportable for the U.S. except for primary sites C700-C729, C751-C753.
Canada, refer to your specific province for reportability requirements.
Canada, refer to your specific province for reportability requirements.
Abstractor Notes
(This code is effective for cases diagnosed 2021 and later.)
Monoclonal B-cell lymphocytosis, non-chronic lymphocytic leukemia (CLL)-type is part of the Mature B-cell neoplasms lineage table in the WHO 5th edition of Hematolymphoid Tumors. (See Appendix B in the Hematopoietic Manual, Table B15)
MBL is present in the peripheral blood and may be detectable in bone marrow and secondary lymphoid tissue. It is usually found incidentally when workup is done for other conditions.
There are two types of MBL
1. Monoclonal B-cell lymphocytosis, chronic lymphocytic leukemia type (9823/1)
2. Monoclonal B-cell lymphocytosis, non–chronic lymphocytic leukemia type (9591/1)
Monoclonal B-cell lymphocytosis, non-chronic lymphocytic leukemia (CLL)-type is part of the Mature B-cell neoplasms lineage table in the WHO 5th edition of Hematolymphoid Tumors. (See Appendix B in the Hematopoietic Manual, Table B15)
MBL is present in the peripheral blood and may be detectable in bone marrow and secondary lymphoid tissue. It is usually found incidentally when workup is done for other conditions.
There are two types of MBL
1. Monoclonal B-cell lymphocytosis, chronic lymphocytic leukemia type (9823/1)
2. Monoclonal B-cell lymphocytosis, non–chronic lymphocytic leukemia type (9591/1)
Alternate Names
Definition
Monoclonal B-cell lymphocytosis (MBL) is an asymptomatic condition characterized by the presence of a monoclonal B-cell population in the absence of lymphadenopathy, organomegaly, and any features diagnostic of another B-cell lymphoproliferative disorder (B-LPD). (WHO 5th edition)
Corresponding ICD-10 Codes (Cause of Death codes only)
D72.8 Other specified disorders of white blood cells
Corresponding ICD-10-CM Codes (U.S. only)
D72.820 Lymphocytosis (symptomatic) (effective October 01, 2015)
Sources
WHO Classification of Tumours Editorial Board. Haematolymphoid tumours. Lyon (France): International Agency for Research on Cancer; 2024. (WHO classification of tumours series, 5th ed.; vol. 11). https://publications.iarc.who.int/637.
Section: Preneoplastic and neoplastic small lymphocytic proliferations
Pages: Part B: 366-367
Section: Preneoplastic and neoplastic small lymphocytic proliferations
Pages: Part B: 366-367
International Classification of Diseases for Oncology, 3rd edition (including revisions). Geneva: World Health Organization, 2001, 2011, 2020.
Section: ICD-O-3.2 (2020) Morphological Codes
Pages: http://www.iacr.com.fr/index.php?option=com_content&view=category&layout=blog&id=100&Itemid=577
Section: ICD-O-3.2 (2020) Morphological Codes
Pages: http://www.iacr.com.fr/index.php?option=com_content&view=category&layout=blog&id=100&Itemid=577
