|
tgDCC-E1A
|
Biologic therapy (BRM, immunotherapy)
|
Head & neck,
ovarian cancer
|
Yes
|
|
sibrotuzumab
|
Chemotherapy
|
Breast,
colorectal,
lung,
other cancer,
pancreatic
|
Yes
|
|
sT4
|
AIDS drug
|
|
No
|
|
rgp120/HIV-1 (IIIB)
|
AIDS drug
|
|
No
|
|
rgp120 CHO
|
AIDS drug
|
|
No
|
|
recMAGE-A3+AS15
|
Biologic therapy (BRM, immunotherapy)
|
Melanoma,
NSCLC
|
Yes
|
|
radiotherapy
|
Radiation
|
|
Yes
|
|
rV-MART-1
|
Biologic therapy (BRM, immunotherapy)
|
Skin cancer
|
Yes
|
|
rV-GP100
|
Biologic therapy (BRM, immunotherapy)
|
Skin cancer
|
Yes
|
|
rF-gp100
|
Biologic therapy (BRM, immunotherapy)
|
Skin cancer
|
Yes
|
|
rF-Tyrosine Vaccine
|
Biologic therapy (BRM, immunotherapy)
|
Skin cancer
|
Yes
|
|
rF-Mgp100
|
Biologic therapy (BRM, immunotherapy)
|
Skin cancer
|
Yes
|
|
rF-MART-1
|
Biologic therapy (BRM, immunotherapy)
|
Skin cancer
|
Yes
|
|
rCD4
|
AIDS drug
|
|
No
|
|
pivaloyloxymethylbutyrate
|
Chemotherapy
|
Liver,
lung cancer
|
Yes
|
|
p53 Tumor Suppressor Gene
|
Biologic therapy (BRM, immunotherapy)
|
Head & neck,
liver,
ovarian cancer
|
Yes
|
|
hypoxia-inducible factor-2 alpha (HIF-2α) inhibitor MK-6482
|
Chemotherapy
|
Kidney
|
Yes
|
|
hR3
|
Biologic therapy (BRM, immunotherapy)
|
Head & neck cancer
|
Yes
|
|
hIL13-PE38QQR (ligand targeted toxin)
|
Chemotherapy
|
Kidney cancer
|
Yes
|
|
gp100 Plasmid Vector in Gold Particles
|
Biologic therapy (BRM, immunotherapy)
|
Skin cancer
|
Yes
|
|
gp100 Peptide Vaccine
|
Biologic therapy (BRM, immunotherapy)
|
Skin cancer
|
Yes
|
|
gp100 DNA Vaccine
|
Biologic therapy (BRM, immunotherapy)
|
Skin cancer
|
Yes
|
|
diazooxonorleucine
|
Chemotherapy
|
Skin cancer
|
Yes
|
|
dabrafenib
|
Chemotherapy
|
Melanoma,
Lung,
Thyroid
|
Yes
|
|
cAC10-vcMMAE(4)
|
Chemotherapy
|
Hodgkin lymphoma
|
Yes
|
|
avutometinib/defactinib
|
Chemotherapy
|
Ovary,
|
Yes
|
|
anti-Tac(Fv)-PE38 (immunotoxin)
|
Biologic therapy (BRM, immunotherapy)
|
Leukemia
|
Yes
|
|
anti-CD72
|
Biologic therapy (BRM, immunotherapy)
|
Leukemia
|
Yes
|
|
Zynyz
|
Biologic therapy (BRM, immunotherapy)
|
|
Yes
|
|
Zynlonta
|
Biologic therapy (BRM, immunotherapy)
|
|
Yes
|
|
Zykadia
|
Chemotherapy
|
Lung
|
Yes
|
|
Zydelig
|
Chemotherapy
|
|
Yes
|
|
Zosuquidar
|
Ancillary Agent
|
|
No
|
|
Zorubicin
|
Chemotherapy
|
|
Yes
|
|
Zongertinib
|
Chemotherapy
|
lung
|
Yes
|
|
Zoledronic acid
|
Ancillary Agent
|
|
No
|
|
Zoladex
|
Hormones and hormonal mechanisms
|
Breast,
prostate cancer
|
Yes
|
|
Zirabev
|
Biologic therapy (BRM, immunotherapy)
|
|
Yes
|
|
Zinostatin
|
Chemotherapy
|
|
Yes
|
|
Ziihera
|
Biologic therapy (BRM, immunotherapy)
|
Bile ducts, Gall bladder
|
Yes
|
|
Ziftomenib
|
Chemotherapy
|
|
Yes
|
|
Ziextenzo
|
Ancillary Agent
|
|
No
|
|
Zidovudine
|
AIDS drug
|
|
No
|
|
Zevalin
|
Radiation
|
Lymphoma
|
Yes
|
|
Zeniplatin
|
Chemotherapy
|
|
Yes
|
|
Zanubrutinib
|
Chemotherapy
|
|
Yes
|
|
Zanolimumab
|
Biologic therapy (BRM, immunotherapy)
|
Cutaneous T-cell lymphoma,
mycosis fungoides
|
Yes
|
|
Zamyl
|
Biologic therapy (BRM, immunotherapy)
|
Leukemia
|
Yes
|
|
Zalutumumab
|
Chemotherapy
|
H&N,
NSCLC
|
Yes
|
|
Zaltrap
|
Chemotherapy
|
Colorectal
|
Yes
|
|
Zalcitabine
|
AIDS drug
|
|
No
|
|
ZYC300
|
Biologic therapy (BRM, immunotherapy)
|
Breast,
colon,
kidney,
ovary,
prostate
|
Yes
|
|
ZK Epothilone
|
Chemotherapy
|
breast,
Prostate
|
Yes
|
|
ZD6126
|
Chemotherapy
|
Breast,
cervical,
endometrial,
other cancer,
ovarian
|
Yes
|
|
ZD0473
|
Chemotherapy
|
Lung,
ovarian Cancer
|
Yes
|
|
Yoshi-864
|
Chemotherapy
|
|
Yes
|
|
Yescarta
|
Biologic therapy (BRM, immunotherapy)
|
|
Yes
|
|
YMB-1003MAb
|
Biologic therapy (BRM, immunotherapy)
|
Colorectal cancer
|
Yes
|
|
YM598
|
Chemotherapy
|
Pancreatic caner
|
Yes
|
|
Y-CEA-Cide
|
Radiation
|
Pancreatic cancer
|
Yes
|
|
Xyotax
|
Chemotherapy
|
Breast,
colorectal,
lung,
ovarian cancer
|
Yes
|
|
Xpovio
|
Chemotherapy
|
|
Yes
|
|
Xofigo
|
Radiation
|
Metastatic prostate cancer
|
Yes
|
|
Xermelo
|
Ancillary Agent
|
|
No
|
|
Xerecept
|
Ancillary Agent
|
Brain cancer
|
Yes
|
|
Xcytrin
|
Ancillary Agent
|
Brain,
Lung cancer
|
No
|
|
Xcellerate
|
Biologic therapy (BRM, immunotherapy)
|
Kidney,
prostate cancer
|
Yes
|
|
Xalkori
|
Chemotherapy
|
Non Small Cell Lung Cancer (NSCLC)
|
Yes
|
|
Xaliproden
|
Ancillary Agent
|
|
No
|
|
XL-888
|
Chemotherapy
|
Failed first course,
melanoma,
mets,
NSCLC,
or unresectable: breast
|
Yes
|
|
XL-765
|
Chemotherapy
|
breast,
Malignant glioma,
NSCLC
|
Yes
|
|
XL-281
|
Chemotherapy
|
colorectal,
melanoma,
NSC,
papillary thyroid
|
Yes
|
|
XL-184
|
Chemotherapy
|
GBM,
NSCLC,
solid tumors,
Thyroid
|
Yes
|
|
XL-147
|
Chemotherapy
|
Advanced Endometrium,
lymphoma,
Mets breast,
NSCLC,
ovarian
|
Yes
|
|
XL-139
|
Chemotherapy
|
GE and esophageal adenocarcinoma,
inoperable stomach,
mets gastric,
multiiple myeloma,
SCLC
|
Yes
|
|
XK469
|
Chemotherapy
|
advanced solid tumors,
Lymphoma
|
Yes
|
|
XK-469
|
Chemotherapy
|
Other cancer
|
Yes
|
|
XIAP antisense
|
Chemotherapy
|
AML
|
Yes
|
|
Wobenzym
|
AIDS drug
|
|
No
|
|
Warfarin Sodium
|
Ancillary Agent
|
|
See Remarks
|
|
WX-UK1
|
Chemotherapy
|
Gastric,
ovarian,
pancreatic cancer
|
Yes
|
|
WT-1 peptide vaccine
|
Biologic therapy (BRM, immunotherapy)
|
Pleura
|
See Remarks
|
|
WR 6026
|
AIDS drug
|
|
No
|
|
WR 2026
|
Ancillary Agent
|
|
No
|
|
WF10
|
AIDS drug
|
Lymphoma
|
No
|
|
Vyxeos
|
Chemotherapy
|
|
Yes
|
|
Vyloy
|
Biologic therapy (BRM, immunotherapy)
|
Stomach, GE junction
|
Yes
|
|
Vorinostat
|
Chemotherapy
|
advanced solid tumors,
colorectal,
CTCL,
Leukemia,
other cancer
|
Yes
|
|
Voriconazole
|
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Voraxase
|
Ancillary Agent
|
|
No
|
|
Voranigo
|
Chemotherapy
|
CNS
|
Yes
|
|
Vonjo
|
Chemotherapy
|
Bone marrow
|
Yes
|
|
Volasertib
|
Chemotherapy
|
AML trials,
Ovarian trials,
Solid tumors trials
|
Yes
|
|
Vitaxin
|
Chemotherapy
|
Colorectal,
other cancer
|
Yes
|
|
Vitamin E
|
Ancillary Agent
|
|
No
|
|
Vitamin D
|
Ancillary Agent
|
|
No
|
|
Vistogard
|
Ancillary Agent
|
|
No
|
|
Vismodegib
|
Chemotherapy
|
Basal cell carcinoma, skin
|
Yes
|
|
Virulizin
|
Biologic therapy (BRM, immunotherapy)
|
Pancreatic cancer
|
Yes
|
|
Vinzolidine Sulfate
|
Chemotherapy
|
|
Yes
|