A drug administered to a patient for treatment, listed in SEER*Rx as a chemotherapeutic, hormonal or immunotherapy agent should be coded under chemotherapy [#1390], hormone therapy [#1400] or immunotherapy [#1410] regardless of the primary site(s) listed in SEER*Rx for that agent. Do not code under the data item, Other Therapy [NAACCR #1420]. Refer to the 2026 SEER manual for more information.

Name Category Primary Site Code?
Lenalidomide Biologic therapy (BRM, immunotherapy) 5q- MDS, CLL, MDS, Multiple myeloma, melanoma, Lymphoma Yes
Intravenous Immune Globulin Biologic therapy (BRM, immunotherapy) AIDS, CLL, Opportunistic infection Yes
Milodistim Ancillary Agent AIDS, Opportunistic infection No
Poly I: Poly C AIDS drug AIDS, Opportunistic infection No
Interferon alfacon-1 Biologic therapy (BRM, immunotherapy) AIDS, Opportunistic infection Yes
Sulfamethoxazole Ancillary Agent, AIDS drug AIDS, Opportunistic infection No
Interleukin-6 Biologic therapy (BRM, immunotherapy) AIDS, Opportunistic infection Yes
Trimethoprim Ancillary Agent, AIDS drug AIDS, Opportunistic infection No
Lomotil Ancillary Agent, AIDS drug AIDS, Opportunistic infection No
Interleukin-1 beta Biologic therapy (BRM, immunotherapy) AIDS, Opportunistic infection Yes
Miconazole AIDS drug AIDS, Opportunistic infection No
Interleukin-10 Biologic therapy (BRM, immunotherapy) AIDS, Opportunistic infection Yes
Interferon Alfa-2a Biologic therapy (BRM, immunotherapy) AIDS, Opportunistic infection Yes
Erythropoietin Ancillary Agent AIDS, Opportunistic infection No
Interferon gamma-1b Biologic therapy (BRM, immunotherapy) AIDS, Opportunistic infection Yes
CSF-2 Ancillary Agent AIDS, Opportunistic infection No
Mupirocin Ancillary Agent AIDS, Opportunistic infection No
Lentinan Biologic therapy (BRM, immunotherapy), AIDS drug AIDS, Opportunistic infection Yes
Metronidazole Ancillary Agent, AIDS drug, Other therapy AIDS, Opportunistic infection See Remarks
Interferon beta-1b Ancillary Agent AIDS, Opportunistic infection No
Voriconazole AIDS drug AIDS, Opportunistic infection No
Acetylcysteine Ancillary Agent AIDS, Opportunistic infection No
Malathion AIDS drug AIDS, Opportunistic infection No
Mitoguazone Chemotherapy AIDS, Opportunistic infection Yes
Sulfadiazine Ancillary Agent, AIDS drug AIDS, Opportunistic infection No
Spiramycin Ancillary Agent, AIDS drug AIDS, Opportunistic infection No
Tioconazole AIDS drug AIDS, Opportunistic infection No
Sparfloxacin Ancillary Agent, AIDS drug AIDS, Opportunistic infection No
Recombinant Soluble Human CD4 Biologic therapy (BRM, immunotherapy) AIDS, Opportunistic infection Yes
Interferon Alfa-n1 Biologic therapy (BRM, immunotherapy) AIDS, Opportunistic infection Yes
Letrazuril AIDS drug AIDS, Opportunistic infection No
Inolimomab AIDS drug AIDS, Opportunistic infection Yes
Interferon natural Biologic therapy (BRM, immunotherapy) AIDS, Opportunistic infection Yes
Mexiletine Hydrochloride AIDS drug AIDS, Opportunistic infection No
Nitrofurazone Ancillary Agent AIDS, Opportunistic infection No
Somatrem Hormones and hormonal mechanisms AIDS, Opportunistic infection Yes
Interleukin-2 Biologic therapy (BRM, immunotherapy) AIDS, breast, head & neck cancer, leukemia, lymphoma, Opportunistic infection Yes
SGN-30 Chemotherapy ALCL, Lymphoma Yes
SCH-900776 Chemotherapy ALL, AML, CML, Hodgkin, NHL Yes
Clofarabine Chemotherapy ALL, AML, CML, Leukemia, lymphoma, myeloproliferative disease, other cancer Yes
Cytarabine Chemotherapy ALL, AML, CML, head and neck, Hodgkin's disease, leukemia, Meningeal leukemia, NHL Yes
Treosulfan Chemotherapy ALL, AML, MDS No
Onco-TCS Chemotherapy ALL, leukemia, Lung cancer, lymphoma Yes
XIAP antisense Chemotherapy AML Yes
SKI-606 Chemotherapy AML Yes
Cyclopentenyl-cytosine Chemotherapy AML Yes
Valproic acid Chemotherapy AML, CLL, lymphocytic lymphoma See Remarks
SB-1518 Chemotherapy AML, CML, MDS Yes
Lovastatin Chemotherapy AML, Hepatoma, stomach Yes
LBH-589 Chemotherapy AML, Hodgkin lymphoma, MDS, multiple myeloma Yes
Cloretazine Chemotherapy AML, Leukemia, other cancers, SCLC Yes
MGCD0103 Chemotherapy AML, MDS Yes
Lintuzumab Chemotherapy AML, MDS Yes
LY-2181308 Chemotherapy AML, Prostate Yes
Lestaurinib Chemotherapy AML, leukemia, other cancer, Pancreatic, prostate Yes
Volasertib Chemotherapy AML trials, Ovarian trials, Solid tumors trials Yes
Tretinoin Differentiation inducing agent Acute Promyelocytic leukemia (APL), AIDS, head & neck cancer, Opportunistic infection See Remarks
Asparaginase Chemotherapy Acute lymphoblastic leukemia (ALL) Yes
Erwinaze Chemotherapy Acute lymphoblastic leukemia (ALL) Yes
Omacetaxine Chemotherapy Acute lymphoblastic leukemia (ALL), Acute myelogenous leukemia (AML), Chronic myelogenous leukemia (CML), Myelodysplastic syndrome (MDS) Yes
Idarubicin Chemotherapy Acute lymphoblastic leukemia (ALL), Acute myelogenous leukemia (AML), Chronic myelogenous leukemia in blast crises, Myelodysplastic syndromes (MDS) Yes
Methotrexate Chemotherapy Acute lymphoblastic leukemia (ALL), Bladder cancer, Breast, Gestational trophoblastic cancer, head & neck cancer, lymphoma, Meningeal leukemia, Non-Hodgkin lymphoma, Osteogenic sarcoma, Primary CNS lymphoma Yes
Roscovitine Chemotherapy Acute myelogenous leukemia (AML), B-cell lymphomas, Non small cell lung cancer (NSCLC) Yes
Mitoxantrone Chemotherapy Acute myelogenous leukemia (AML), Breast, Non-Hodgkin lymphoma, Prostate- advanced hormone-refractory Yes
Vanflyta Chemotherapy Acute myeloid leukemia, AML Yes
KW-0761 Chemotherapy Adult T-cell leukemia/lymphoma, peripheral T-cell leukemia/lymphoma Yes
XL-147 Chemotherapy Advanced Endometrium, lymphoma, Mets breast, NSCLC, ovarian Yes
Tetrahydrouridine Chemotherapy Advanced solid tumors Yes
Carboplatin Chemotherapy All cancers Yes
Brentuximab vedotin Biologic therapy (BRM, immunotherapy) Anaplastic large cell lymphoma (ALCL), Hodgkin Lymphoma Yes
Norethandrolone Hormones and hormonal mechanisms Aplastic anemia Yes
Ketoconazole Hormones and hormonal mechanisms As a testosterone blocker for advanced prostate cancer, as an antifungal for AIDS, opportunistic infections Yes
Flavopiridol Chemotherapy B-cell CLL, Colorectal, lung, other cancer, prolymphocytic leukemia arising from CLL, small lymphocytic lymphoma Yes
MEDI-551 Biologic therapy (BRM, immunotherapy) B-cell malignancies Yes
Ibrutinib Chemotherapy B-cell malignancies, CLL, Mantle cell lymphoma, Multiple myeloma, NHL, Waldentrom macroglobulinemia (WM), diffuese B-cell lymphoma, SLL Yes
Vismodegib Chemotherapy Basal cell carcinoma, skin Yes
Propranolol Other therapy Benign hemangioma No
Ziihera Biologic therapy (BRM, immunotherapy) Bile ducts, Gall bladder Yes
Ethylchlorformate Biologic therapy (BRM, immunotherapy) Bladder Yes
Erdafitinib Chemotherapy Bladder Yes
Bropirimine Biologic therapy (BRM, immunotherapy) Bladder Yes
Enfortumab vedotin Biologic therapy (BRM, immunotherapy) Bladder Yes
Padcev Biologic therapy (BRM, immunotherapy) Bladder Yes
Jelmyto Chemotherapy Bladder Yes
Anktiva Biologic therapy (BRM, immunotherapy) Bladder Yes
Gemcitabine Chemotherapy Bladder, Breast, Lung-NSCLC, Ovary, Pancreas, Soft Tissue Sarcoma Yes
Ifosfamide Chemotherapy Bladder, Cervical cancer, Ewing sarcoma, Head and Neck, Hodgkin lymphoma, Non-Hodgkin lymphoma, Non-small cell and small cell lung cancer, Soft tissue sarcoma, osteogenic sarcoma, Testicular cancer Yes
Durvalumab Biologic therapy (BRM, immunotherapy) Bladder, Lung, Biliary tract, Endometrium, Liver, Esophagus and gastroesophageal junction Yes
Atezolizumab Biologic therapy (BRM, immunotherapy) Bladder, Lung, Liver, Breast, Soft tissue Yes
Diaziquone Chemotherapy Bladder, brain, skin cancer Yes
Eflornithine Chemotherapy Bladder, brain (glioblastoma), childhood leukemia, CML, skin cancer Yes
TOCOSOL Chemotherapy Bladder, breast, colorectal, lung, ovarian cancers Yes
Cancer Vaccine Biologic therapy (BRM, immunotherapy) Bladder, breast, kidney, ovarian, skin cancer Yes
Doxorubicin Chemotherapy Bladder, breast, liver, multiple myeloma, ovarian, pancreatic, prostate cancer Yes
Vinflunine Chemotherapy Bladder, breast, lung, other Yes
Celebrex Ancillary Agent Bladder, breast cancer No
Cisplatin Chemotherapy Bladder, ovarian, testicular cancer Yes
Apaziquone Ancillary Agent, Chemotherapy Bladder cancer See Remarks
Tempostatin Chemotherapy Bladder cancer Yes
Levulan Ancillary Agent Bladder cancer No
Glossary