|
Lenalidomide
|
Biologic therapy (BRM, immunotherapy)
|
5q- MDS,
CLL,
MDS,
Multiple myeloma,
melanoma,
Lymphoma
|
Yes
|
|
Intravenous Immune Globulin
|
Biologic therapy (BRM, immunotherapy)
|
AIDS,
CLL,
Opportunistic infection
|
Yes
|
|
Milodistim
|
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
|
Poly I: Poly C
|
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Interferon alfacon-1
|
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
|
Sulfamethoxazole
|
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Interleukin-6
|
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
|
Trimethoprim
|
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Lomotil
|
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Interleukin-1 beta
|
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
|
Miconazole
|
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Interleukin-10
|
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
|
Interferon Alfa-2a
|
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
|
Erythropoietin
|
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
|
Interferon gamma-1b
|
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
|
CSF-2
|
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
|
Mupirocin
|
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
|
Lentinan
|
Biologic therapy (BRM, immunotherapy),
AIDS drug
|
AIDS,
Opportunistic infection
|
Yes
|
|
Metronidazole
|
Ancillary Agent,
AIDS drug,
Other therapy
|
AIDS,
Opportunistic infection
|
See Remarks
|
|
Interferon beta-1b
|
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
|
Voriconazole
|
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Acetylcysteine
|
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
|
Malathion
|
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Mitoguazone
|
Chemotherapy
|
AIDS,
Opportunistic infection
|
Yes
|
|
Sulfadiazine
|
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Spiramycin
|
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Tioconazole
|
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Sparfloxacin
|
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Recombinant Soluble Human CD4
|
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
|
Interferon Alfa-n1
|
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
|
Letrazuril
|
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Inolimomab
|
AIDS drug
|
AIDS,
Opportunistic infection
|
Yes
|
|
Interferon natural
|
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
|
Mexiletine Hydrochloride
|
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
|
Nitrofurazone
|
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
|
Somatrem
|
Hormones and hormonal mechanisms
|
AIDS,
Opportunistic infection
|
Yes
|
|
Interleukin-2
|
Biologic therapy (BRM, immunotherapy)
|
AIDS,
breast,
head & neck cancer,
leukemia,
lymphoma,
Opportunistic infection
|
Yes
|
|
SGN-30
|
Chemotherapy
|
ALCL,
Lymphoma
|
Yes
|
|
SCH-900776
|
Chemotherapy
|
ALL,
AML,
CML,
Hodgkin,
NHL
|
Yes
|
|
Clofarabine
|
Chemotherapy
|
ALL,
AML,
CML,
Leukemia,
lymphoma,
myeloproliferative disease,
other cancer
|
Yes
|
|
Cytarabine
|
Chemotherapy
|
ALL,
AML,
CML,
head and neck,
Hodgkin's disease,
leukemia,
Meningeal leukemia,
NHL
|
Yes
|
|
Treosulfan
|
Chemotherapy
|
ALL,
AML,
MDS
|
No
|
|
Onco-TCS
|
Chemotherapy
|
ALL,
leukemia,
Lung cancer,
lymphoma
|
Yes
|
|
XIAP antisense
|
Chemotherapy
|
AML
|
Yes
|
|
SKI-606
|
Chemotherapy
|
AML
|
Yes
|
|
Cyclopentenyl-cytosine
|
Chemotherapy
|
AML
|
Yes
|
|
Valproic acid
|
Chemotherapy
|
AML,
CLL,
lymphocytic lymphoma
|
See Remarks
|
|
SB-1518
|
Chemotherapy
|
AML,
CML,
MDS
|
Yes
|
|
Lovastatin
|
Chemotherapy
|
AML,
Hepatoma,
stomach
|
Yes
|
|
LBH-589
|
Chemotherapy
|
AML,
Hodgkin lymphoma,
MDS,
multiple myeloma
|
Yes
|
|
Cloretazine
|
Chemotherapy
|
AML,
Leukemia,
other cancers,
SCLC
|
Yes
|
|
MGCD0103
|
Chemotherapy
|
AML,
MDS
|
Yes
|
|
Lintuzumab
|
Chemotherapy
|
AML,
MDS
|
Yes
|
|
LY-2181308
|
Chemotherapy
|
AML,
Prostate
|
Yes
|
|
Lestaurinib
|
Chemotherapy
|
AML,
leukemia,
other cancer,
Pancreatic,
prostate
|
Yes
|
|
Volasertib
|
Chemotherapy
|
AML trials,
Ovarian trials,
Solid tumors trials
|
Yes
|
|
Tretinoin
|
Differentiation inducing agent
|
Acute Promyelocytic leukemia (APL),
AIDS,
head & neck cancer,
Opportunistic infection
|
See Remarks
|
|
Asparaginase
|
Chemotherapy
|
Acute lymphoblastic leukemia (ALL)
|
Yes
|
|
Erwinaze
|
Chemotherapy
|
Acute lymphoblastic leukemia (ALL)
|
Yes
|
|
Omacetaxine
|
Chemotherapy
|
Acute lymphoblastic leukemia (ALL),
Acute myelogenous leukemia (AML),
Chronic myelogenous leukemia (CML),
Myelodysplastic syndrome (MDS)
|
Yes
|
|
Idarubicin
|
Chemotherapy
|
Acute lymphoblastic leukemia (ALL),
Acute myelogenous leukemia (AML),
Chronic myelogenous leukemia in blast crises,
Myelodysplastic syndromes (MDS)
|
Yes
|
|
Methotrexate
|
Chemotherapy
|
Acute lymphoblastic leukemia (ALL),
Bladder cancer,
Breast,
Gestational trophoblastic cancer,
head & neck cancer,
lymphoma,
Meningeal leukemia,
Non-Hodgkin lymphoma,
Osteogenic sarcoma,
Primary CNS lymphoma
|
Yes
|
|
Roscovitine
|
Chemotherapy
|
Acute myelogenous leukemia (AML),
B-cell lymphomas,
Non small cell lung cancer (NSCLC)
|
Yes
|
|
Mitoxantrone
|
Chemotherapy
|
Acute myelogenous leukemia (AML),
Breast,
Non-Hodgkin lymphoma,
Prostate- advanced hormone-refractory
|
Yes
|
|
Vanflyta
|
Chemotherapy
|
Acute myeloid leukemia,
AML
|
Yes
|
|
KW-0761
|
Chemotherapy
|
Adult T-cell leukemia/lymphoma,
peripheral T-cell leukemia/lymphoma
|
Yes
|
|
XL-147
|
Chemotherapy
|
Advanced Endometrium,
lymphoma,
Mets breast,
NSCLC,
ovarian
|
Yes
|
|
Tetrahydrouridine
|
Chemotherapy
|
Advanced solid tumors
|
Yes
|
|
Carboplatin
|
Chemotherapy
|
All cancers
|
Yes
|
|
Brentuximab vedotin
|
Biologic therapy (BRM, immunotherapy)
|
Anaplastic large cell lymphoma (ALCL),
Hodgkin Lymphoma
|
Yes
|
|
Norethandrolone
|
Hormones and hormonal mechanisms
|
Aplastic anemia
|
Yes
|
|
Ketoconazole
|
Hormones and hormonal mechanisms
|
As a testosterone blocker for advanced prostate cancer,
as an antifungal for AIDS,
opportunistic infections
|
Yes
|
|
Flavopiridol
|
Chemotherapy
|
B-cell CLL,
Colorectal,
lung,
other cancer,
prolymphocytic leukemia arising from CLL,
small lymphocytic lymphoma
|
Yes
|
|
MEDI-551
|
Biologic therapy (BRM, immunotherapy)
|
B-cell malignancies
|
Yes
|
|
Ibrutinib
|
Chemotherapy
|
B-cell malignancies,
CLL,
Mantle cell lymphoma,
Multiple myeloma,
NHL,
Waldentrom macroglobulinemia (WM),
diffuese B-cell lymphoma,
SLL
|
Yes
|
|
Vismodegib
|
Chemotherapy
|
Basal cell carcinoma, skin
|
Yes
|
|
Propranolol
|
Other therapy
|
Benign hemangioma
|
No
|
|
Ziihera
|
Biologic therapy (BRM, immunotherapy)
|
Bile ducts, Gall bladder
|
Yes
|
|
Ethylchlorformate
|
Biologic therapy (BRM, immunotherapy)
|
Bladder
|
Yes
|
|
Erdafitinib
|
Chemotherapy
|
Bladder
|
Yes
|
|
Bropirimine
|
Biologic therapy (BRM, immunotherapy)
|
Bladder
|
Yes
|
|
Enfortumab vedotin
|
Biologic therapy (BRM, immunotherapy)
|
Bladder
|
Yes
|
|
Padcev
|
Biologic therapy (BRM, immunotherapy)
|
Bladder
|
Yes
|
|
Jelmyto
|
Chemotherapy
|
Bladder
|
Yes
|
|
Anktiva
|
Biologic therapy (BRM, immunotherapy)
|
Bladder
|
Yes
|
|
Gemcitabine
|
Chemotherapy
|
Bladder,
Breast,
Lung-NSCLC,
Ovary,
Pancreas,
Soft Tissue Sarcoma
|
Yes
|
|
Ifosfamide
|
Chemotherapy
|
Bladder,
Cervical cancer,
Ewing sarcoma,
Head and Neck,
Hodgkin lymphoma,
Non-Hodgkin lymphoma,
Non-small cell and small cell lung cancer,
Soft tissue sarcoma, osteogenic sarcoma,
Testicular cancer
|
Yes
|
|
Durvalumab
|
Biologic therapy (BRM, immunotherapy)
|
Bladder,
Lung,
Biliary tract,
Endometrium,
Liver,
Esophagus and gastroesophageal junction
|
Yes
|
|
Atezolizumab
|
Biologic therapy (BRM, immunotherapy)
|
Bladder,
Lung,
Liver,
Breast,
Soft tissue
|
Yes
|
|
Diaziquone
|
Chemotherapy
|
Bladder,
brain,
skin cancer
|
Yes
|
|
Eflornithine
|
Chemotherapy
|
Bladder,
brain (glioblastoma),
childhood leukemia,
CML,
skin cancer
|
Yes
|
|
TOCOSOL
|
Chemotherapy
|
Bladder,
breast,
colorectal,
lung,
ovarian cancers
|
Yes
|
|
Cancer Vaccine
|
Biologic therapy (BRM, immunotherapy)
|
Bladder,
breast,
kidney,
ovarian,
skin cancer
|
Yes
|
|
Doxorubicin
|
Chemotherapy
|
Bladder,
breast,
liver,
multiple myeloma,
ovarian,
pancreatic,
prostate cancer
|
Yes
|
|
Vinflunine
|
Chemotherapy
|
Bladder,
breast,
lung,
other
|
Yes
|
|
Celebrex
|
Ancillary Agent
|
Bladder,
breast cancer
|
No
|
|
Cisplatin
|
Chemotherapy
|
Bladder,
ovarian,
testicular cancer
|
Yes
|
|
Apaziquone
|
Ancillary Agent,
Chemotherapy
|
Bladder cancer
|
See Remarks
|
|
Tempostatin
|
Chemotherapy
|
Bladder cancer
|
Yes
|
|
Levulan
|
Ancillary Agent
|
Bladder cancer
|
No
|
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