Name

Cyramza

Alternate Names

Ramucirumab

Abbreviations

None

Category

Biologic therapy (BRM, immunotherapy)

Subcategory

Antiangiogenesis
Monoclonal antibody

NSC Number

749128

Primary Site

Brain, CNS
Breast
Colorectal
Gastric, GE
Liver
Non-small cell lung cancer (NSCLC)
Ovarian
Prostate
Renal Cell Carcinoma (RCC)
Urinary

Histology

None

Remarks

May 29, 2020: The FDA approved ramucirumab (CYRAMZA) in combination with erlotinib for first-line treatment of metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) mutations.

May 10, 2019: FDA approved ramucirumab (CYRAMZA) as a single agent for hepatocellular carcinoma (HCC) in patients who have an alpha fetoprotein (AFP) of ≥ 400 ng/mL and have been previously treated with sorafenib.

FDA approved ramucirumab for use as a single agent for the treatment of patients with advanced or metastatic gastric or gastroesophageal junction adenocarcinoma with disease progression on or after prior treatment with fluoropyrimidine or platinum containing chemotherapy.

Coding

This drug should be coded
Glossary