Name

Tretinoin

Alternate Names

Aberel
Airol
All-trans-retinoic acid
Avita
Dermairol
Eudyna
Renova
Retin-A
Retinoic acid
Retisol-A
Stieva-A
Vesanoid
Vitamin A Acid
Vitinoin

Abbreviations

ATRA
Vit A

Category

Differentiation inducing agent

Subcategory

None

NSC Number

122758

Primary Site

Acute Promyelocytic leukemia (APL)
AIDS

Histology

None

Remarks

Tretinoin is FDA approved for treatment of acute promyelocytic leukemia (APL). It is a retinoid/differentiation agent and at this time the precise mechanism of action has not been fully elucidated so it cannot be assigned to chemotherapy, hormone or BRM/immunotherapy. Code this agent as treatment in the "Other Therapy" data field (using code 1).

Phase II (head & neck)
Administered topically, tretinoin stimulates epithelial turnover and reduces epithelial cell cohesiveness. Under investigation for treatment of Kaposi sarcoma lesions. FDA approved therapy of acute promyelocytic leukemia. NCI.Code this agent as treatment in the "Other Therapy" data field (using code 1).

Coding

Please see remarks for additional information
Glossary