Name

Diaziquone

Alternate Names

Aziridinylbenzoquinone
CI 904
CI-904
CI904

Abbreviations

AZQ

Category

Chemotherapy

Subcategory

Alkylating agent

NSC Number

182986

Primary Site

Bladder
brain
skin cancer

Histology

None

Remarks

Phase III Quinone derivative; Intravenous diaziquone has produced objective responses in some patients with brain tumors and head and neck cancer; high response rates have been seen with continuous infusions in acute myelogenous (nonlymphocytic) leukemia, although hematologic toxicity is severe. The drug has been effective intrathecally in meningeal malignancies. However, the overall role of diaziquone in cancer chemo is limited. Ilex Oncology.

Coding

This drug should be coded
Glossary