Name

Megestrol Acetate

Alternate Names

Apo-Megestrol
BDH-1298
Compound 5071
Megace
SC-10363

Abbreviations

None

Category

Hormones and hormonal mechanisms
AIDS drug

Subcategory

Progestin

NSC Number

71423
071423

Primary Site

Uterus
Breast

Histology

None

Remarks

A synthetic progestin; FDA approved indications include palliative treatment in advanced endometrial and breast carcinoma. Also for the treatment of anorexia, cachexia, and significant weight loss in patients with acquired immunodeficiency syndrome; administered orally.

Code Megestrol if given as first course of treatment in advanced/metastatic endometrial or breast cancer, uterine sarcomas (usually in low grade endometrial stromal sarcoma, adenosarcoma, or ER/PR positive uterine sarcomas), or in early stage endometroid carcinoma in which fertility preservation is desired.

Megestrol can be given alone, or in combination with other progestational agents or with chemotherapy.

DO NOT code when given as an appetite stimulant.

Coding

Please see remarks for additional information
Glossary