Name

Vindesine

Alternate Names

Compound 112531
Eldesine
Eldisine
Lilly 99094
LY-099094
Vincaleukoblastine
Vindesine sulfate

Abbreviations

DAVA
DVA

Category

Chemotherapy

Subcategory

Plant alkyloid

NSC Number

245467

Primary Site

None

Histology

None

Remarks

Vindesine has activity in a wide variety of malignancies including colorectal, lung, breast, and esophageal carcinomas; it also has activity in lymphomas and leukemias, glioma, and melanoma. Neurotoxicity (dose-limiting and cumulative) and cross-resistance with vincristine have limited the usefulness of this agent. Although vindesine in combination with cisplatin is one of the most active regimens for non-small cell lung cancer.

Coding

This drug should be coded
Glossary