Vindesine

Name
Vindesine
Alternate Names
Compound 112531
Eldesine
Eldisine
Lilly 99094
LY-099094
Vincaleukoblastine
Vindesine sulfate
Abbreviations
DAVA
DVA
Category
Chemotherapy
Subcategory
Plant alkyloid
NSC Number
245467
Primary Site
None
Histology
None
Remarks
Vindesine has activity in a wide variety of malignancies including colorectal, lung, breast, and esophageal carcinomas; it also has activity in lymphomas and leukemias, glioma, and melanoma. Neurotoxicity (dose-limiting and cumulative) and cross-resistance with vincristine have limited the usefulness of this agent. Although vindesine in combination with cisplatin is one of the most active regimens for non-small cell lung cancer.
Coding
This drug should be coded